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Advances in General and Regional Anaesthesia

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Anesthesiology".

Deadline for manuscript submissions: 26 June 2026 | Viewed by 928

Special Issue Editors


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Guest Editor
1. Department of Emergency Medicine, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-555 Katowice, Poland
2. Department of Anesthesiology and Intensive Care, 5th Regional Hospital, 41-200 Sosnowiec, Poland
Interests: nociception; analgesia; pupillometry

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Guest Editor
Collegium Medicum, WSB University, 41-300 Dabrowa Gornicza, Poland
Interests: cancer; biomarkers; multiomics; machine learning; personalised medicine

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Guest Editor

Special Issue Information

Dear Colleagues,

Monitoring the depth of anaesthesia using digital devices, including bispectral index (BIS), auditory evoked potentials (AEP), entropy EEG, quality of neuromuscular block using NMT, nociception/anti-nociception balance using pupillometry, surgical pleth index (SPI), and nociception level (NoL), is still not routinely used in modern anaesthesia. Therefore, further studies are required to spread modern technologies in anaesthesia. This Special Issue is therefore dedicated to evaluating their potential utility in optimising the guidance of anaesthesia depth and the quality of analgesia in patients undergoing different surgical procedures where analgesia will be achieved intraoperatively using either ultrasound-guided regional, central, or epidural techniques, with adjuvants, or alternatively with intravenous pre-emptive analgesia using non-opioid medication. The expectations of modern societies of the 21st century entail the eradication of adverse events like acute postoperative pain and chronic postoperative pain, haemodynamic instability despite comorbidities, and postoperative nausea and vomiting with the  optimalisation of hospital stay while ensuring economic frugality.

Therefore, this Special Issue is for those who are currently running studies in the field of modern technologies regarding general and regional anaesthesia and their impact on the quality of postoperative care, as well as those performing additional analyses from closed projects regarding the risk factors of the incidence of adverse events in order to design personalised anaesthesia regimens meant to improve outcomes in patients undergoing specific surgical procedures that require an individual approach.

Dr. Michał Jan Stasiowski
Dr. Nikola Zmarzły
Dr. Beniamin Oskar Grabarek
Guest Editors

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Keywords

  • general anaesthesia
  • regional anaesthesia
  • ropivacaine
  • bupivacaine
  • postoperative pain
  • postoperative nausea and vomiting
  • preventive analgesia
  • rescue opioid analgesia
  • total intravenous anaesthesia
  • inhalational anaesthesia

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Published Papers (1 paper)

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Research

13 pages, 454 KB  
Article
Postoperative Nausea and Vomiting After Open Lumbar Discectomy: A Secondary Analysis of a Randomized Trial Using Adequacy of Anesthesia Monitoring
by Michał J. Stasiowski, Karolina Ćmiel-Smorzyk and Nikola Zmarzły
J. Clin. Med. 2026, 15(1), 360; https://doi.org/10.3390/jcm15010360 - 3 Jan 2026
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Abstract
Background/Objectives: Postoperative nausea and vomiting (PONV) remains a frequent and clinically relevant complication following open lumbar discectomy (OLD) under general anesthesia. The present study represents a secondary, post hoc analysis of a randomized controlled trial originally designed to investigate the effects of [...] Read more.
Background/Objectives: Postoperative nausea and vomiting (PONV) remains a frequent and clinically relevant complication following open lumbar discectomy (OLD) under general anesthesia. The present study represents a secondary, post hoc analysis of a randomized controlled trial originally designed to investigate the effects of infiltration anesthesia (IA) on postoperative pain perception and opioid consumption. The objective of this analysis was to explore the incidence of PONV in patients undergoing OLD under adequacy of anesthesia (AoA)-guided general anesthesia, with or without IA. Methods: This secondary analysis included 94 patients undergoing OLD under AoA-guided general anesthesia with fentanyl titration based on the surgical pleth index (SPI). Patients were randomized to receive IA with 0.2% ropivacaine (RF) or bupivacaine (BF) plus 50 µg fentanyl, or no IA (control). PONV was assessed as early (in the post-anesthesia care unit), late (in the neurosurgical ward), and overall (within 48 h postoperatively). Opioid consumption and Apfel risk scores were also analyzed. All analyses related to PONV were exploratory. Results: PONV occurred in 12.8% of patients, with no significant differences between study groups. Postoperative morphine consumption was significantly lower in the RF group than in the control group (2.7 ± 5.3 mg vs. 7.1 ± 5.9 mg; p < 0.05). Higher pre-induction SPI values were observed in patients who experienced early PONV (73.1 ± 9.7 vs. 59.5 ± 17.2; p < 0.05); however, this exploratory finding requires confirmation in larger studies. Conclusions: In this secondary, post hoc analysis, no significant differences in PONV incidence were observed between anesthetic groups in patients undergoing OLD under AoA-guided general anesthesia. The observed association between pre-induction SPI values and early PONV should be interpreted cautiously and requires confirmation in adequately powered prospective studies. Full article
(This article belongs to the Special Issue Advances in General and Regional Anaesthesia)
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