Diagnostic and Therapeutic Challenges in Infective Endocarditis
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".
Deadline for manuscript submissions: 25 September 2025 | Viewed by 954
Special Issue Editor
Interests: cardiovascular infections; infective endocarditis; CIED infection; antimicrobial therapy; gram negative MDR microorganism
Special Issue Information
Dear Colleagues
In the past two decades, Infective Endocarditis (IE) has become an extremely heterogeneous disease, accompanied by an epidemiological shift towards older comorbid patients with valve prosthesis and intracardiac devices that may present with atypical symptoms and uncommon aetiology.
Despite recent advancements in the field, the prognosis of IE remains poor, with an in-hospital mortality rate peaking at 20-25%. Clinicians dealing with cardiovascular infections are called to handle a wide number of diagnostic challenges related to possible inconclusive echocardiography and to difficulties in isolating the causative microorganism. Moreover, patients with IE need a tailored medical and surgical management, sometimes based on low-quality supporting evidence and expert opinions. In this scenario, the multidisciplinary approach represented by the Endocarditis Team is of pivotal importance.
This Special Issue aims to foster interaction between different medical specialists caring for IE patients and to facilitate the spreading of medical knowledge by welcoming the submission of observational, single-centre or multi-centre, retrospective and prospective studies together with case series, clinical case reports and narrative literature reviews focusing on the diagnostic and therapeutic management of IE.
Dr. Lorenzo Bertolino
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- infective endocarditis
- complications
- diagnostic challenges
- therapeutic approach
- epidemiology
- clinical correlates
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
