Diagnostic and Therapeutic Challenges in Infective Endocarditis
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".
Deadline for manuscript submissions: 25 September 2025 | Viewed by 346
Special Issue Editor
Interests: cardiovascular infections; infective endocarditis; CIED infection; antimicrobial therapy; gram negative MDR microorganism
Special Issue Information
Dear Colleagues
In the past two decades, Infective Endocarditis (IE) has become an extremely heterogeneous disease, accompanied by an epidemiological shift towards older comorbid patients with valve prosthesis and intracardiac devices that may present with atypical symptoms and uncommon aetiology.
Despite recent advancements in the field, the prognosis of IE remains poor, with an in-hospital mortality rate peaking at 20-25%. Clinicians dealing with cardiovascular infections are called to handle a wide number of diagnostic challenges related to possible inconclusive echocardiography and to difficulties in isolating the causative microorganism. Moreover, patients with IE need a tailored medical and surgical management, sometimes based on low-quality supporting evidence and expert opinions. In this scenario, the multidisciplinary approach represented by the Endocarditis Team is of pivotal importance.
This Special Issue aims to foster interaction between different medical specialists caring for IE patients and to facilitate the spreading of medical knowledge by welcoming the submission of observational, single-centre or multi-centre, retrospective and prospective studies together with case series, clinical case reports and narrative literature reviews focusing on the diagnostic and therapeutic management of IE.
Dr. Lorenzo Bertolino
Guest Editor
Manuscript Submission Information
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Keywords
- infective endocarditis
- complications
- diagnostic challenges
- therapeutic approach
- epidemiology
- clinical correlates
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