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Total Joint Arthroplasty: Innovations, Outcomes, and Challenges—Second Edition
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Total Joint Arthroplasty: Innovations, Outcomes, and Challenges—Second Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: closed (20 May 2026) | Viewed by 2153

Special Issue Editor

Dr. Hendrik Kohlhof

E-Mail Website
Guest Editor
Department of Orthopaedics, Hand- and Trauma Surgery, St. Antonius Hospital Cologne, Schillerstrasse 23, 50968 Cologne, Germany
Interests: hip; arthroplasty; knee surgery; knee injuries; cartilage; bone; fracture; trauma surgery; sports injuries; perioperative management; revision-arthroplasty; infection; orthogeriatrics; health economics; periprosthetic fractures
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

I am pleased to invite you to contribute to the Special Issue entitled "Total Joint Arthroplasty: Innovations, Outcomes, and Challenges—Second Edition". In the first edition, we published 13 papers. For more details, please visit the following link: https://www.mdpi.com/journal/jcm/special_issues/4794JEXS10.

In recent years, the domain of arthroplasty has witnessed significant advancements, particularly in the area of knee and hip replacements, thereby revolutionizing joint replacement surgeries and improving quality of life for numerous patients suffering from joint degeneration and damage. The field of endoprosthetics is constantly evolving and improving. In particular, new developments in the areas of material research, biomechanics, and surgical approaches, as well as perioperative management and pre- and postoperative patient support, have substantially improved treatment outcomes and patients’ quality of life, in accordance with the demographic change.

With this Special Issue, we aim to highlight the latest advancements in endoprosthetics, as well as the experiences and insights of both patients and medical professionals.

Dr. Hendrik Kohlhof
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • knee and hip replacements
  • joint replacement
  • biomechanics
  • revision arthroplasty
  • orthogeriatrics and perioperative management

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Related Special Issue

Published Papers (2 papers)

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13 pages, 3131 KB  
Article
Management and Treatment Strategies for Distal Tibia and Ankle Infections: Our Clinical Experience
by Antonio Mascio, Chiara Comisi, Carmen Barlotti, Tommaso Greco, Federico Moretti, Virginia Cinelli, Andrea De Fazio, Giovan Giuseppe Mazzella, Giulio Maccauro and Carlo Perisano
J. Clin. Med. 2025, 14(22), 7967; https://doi.org/10.3390/jcm14227967 - 10 Nov 2025
Cited by 1 | Viewed by 1148
Abstract
Background: The management of infections involving the distal tibia and ankle is a significant challenge in orthopedic surgery due to complex anatomy and the high risk of complications. The study aims to present our clinical experience in managing these infections and focusing on [...] Read more.
Background: The management of infections involving the distal tibia and ankle is a significant challenge in orthopedic surgery due to complex anatomy and the high risk of complications. The study aims to present our clinical experience in managing these infections and focusing on surgical strategies, infection control, and functional outcomes over a minimum 24-month follow-up period. Methods: This is an observational, retrospective case series of 17 patients treated for osteoarticular infections of the distal tibia and/or ankle between January 2020 and May 2023, in a second-level referral trauma center. A staged surgical approach was employed, including radical debridement, temporary stabilization with external fixation, and, in most cases, implantation of a cement spacer loaded with antibiotics. Functional outcomes were assessed using scores such as EQ-5D-5L. Results: The cohort was predominantly male (76.5%), with a high prevalence of elevated BMI and comorbidities. Infection onset was most frequently associated with open fractures (64.7%). Staphylococcus aureus was the most common isolated pathogen (41.2%), and infections caused by Gram-negative or multidrug-resistant bacteria were associated with more reoperations. Overall, complications occurred in 10 patients (58.8%), requiring reintervention in 9 patients (52.9%). Limb salvage was achieved in 16 of 17 patients (94.1%). Conclusions: Our study highlights the critical role of a tailored, multidisciplinary approach in managing these complex infections. Meticulous surgical planning and proactive management of complications are essential for optimizing patient outcomes. Full article
(This article belongs to the Special Issue Total Joint Arthroplasty: Innovations, Outcomes, and Challenges—Second Edition)
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Review

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22 pages, 756 KB  
Review
Gender Disparities in Shoulder Pain and Shoulder Surgery: A Current Concepts Review
by Mohammad Daher, Tarishi Parmar, Peter Boufadel, Ziad Zalaquett, Mohamad Y. Fares and Joseph A. Abboud
J. Clin. Med. 2026, 15(5), 1886; https://doi.org/10.3390/jcm15051886 - 1 Mar 2026
Viewed by 663
Abstract
Shoulder pain and shoulder surgery are increasingly prevalent and encompass a broad spectrum of pathologies, including rotator cuff disease, glenohumeral osteoarthritis, and shoulder instability. Growing evidence suggests that gender-related factors influence disease presentation, patient-reported outcomes, and postoperative recovery; however, these effects remain inconsistently [...] Read more.
Shoulder pain and shoulder surgery are increasingly prevalent and encompass a broad spectrum of pathologies, including rotator cuff disease, glenohumeral osteoarthritis, and shoulder instability. Growing evidence suggests that gender-related factors influence disease presentation, patient-reported outcomes, and postoperative recovery; however, these effects remain inconsistently reported across the literature. This current concepts review synthesizes available evidence on the influence of gender on pre-operative characteristics, non-operative management, and postoperative outcomes following common shoulder procedures, including rotator cuff repair, anatomic and reverse shoulder arthroplasty, and surgical stabilization for instability. A comprehensive literature search of PubMed, the Cochrane Library, and Google Scholar was performed for studies published through October 2025, with outcomes assessed using validated instruments such as the Western Ontario Rotator Cuff Index, American Shoulder and Elbow Surgeons score, Constant–Murley score, Simple Shoulder Test, Visual Analog Scale, and Shoulder Pain and Disability Index. Across shoulder pathologies, female patients consistently demonstrated worse pre-operative functional scores, higher pain levels, and greater perceived disability despite similar structural disease severity. Postoperatively, both genders experienced meaningful clinical improvement; however, females often reported higher early postoperative pain and lower absolute functional outcomes, particularly following shoulder arthroplasty for glenohumeral osteoarthritis and surgical treatment of multidirectional instability. In contrast, outcomes following rotator cuff repair and anterior instability stabilization were largely comparable between genders. Recognition of these gender-related differences is essential for individualized patient counseling, expectation setting, and optimization of management strategies, and highlights the need for future studies with robust gender-disaggregated analyses. Full article
(This article belongs to the Special Issue Total Joint Arthroplasty: Innovations, Outcomes, and Challenges—Second Edition)
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