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Accelerating Fracture Healing: Clinical Diagnosis and Treatment
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Accelerating Fracture Healing: Clinical Diagnosis and Treatment

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 25 July 2025 | Viewed by 1160

Special Issue Editor

Dr. Seong-Eun Byun

E-Mail Website
Guest Editor
CHA Bundang Medical Center, School of Medicine, CHA University, Seongnam-si, Republic of Korea
Interests: fracture; trauma surgery; orthopaedic surgery; osteoporosis; bone; hip fracture surgery; fragility fracture

Special Issue Information

Dear Colleagues,

Advancements in imaging modalities, surgical procedures, and fixators have driven significant progress in fracture treatment over the past few decades. These innovations have enabled more precise surgical interventions and improved patient outcomes. The principles of modern fracture treatment, including the preservation of fracture biology, have been firmly established, providing a solid foundation for optimizing healing and restoring function. As a result, most fractures now achieve favorable outcomes with satisfactory functional recovery.

However, despite these advancements, certain fracture types continue to pose significant challenges for orthopedic surgeons. The aging population and changing demographics have led to a rise in fragility fractures, such as atypical femoral fractures, femoral neck fractures, and periprosthetic fractures, which are often linked to bone fragility and comorbid conditions. These fractures are complex in nature, requiring tailored approaches to achieve optimal healing and functional recovery. Furthermore, the management of these fractures often highlights gaps in our current understanding, presenting opportunities for innovation and research.

This Special Issue aims to explore recent advancements in fracture healing techniques, encompassing both diagnostic and therapeutic strategies. We encourage submissions that address cutting-edge approaches, including minimally invasive techniques, clinical applications of novel biomaterials, and individualized treatment, to further enhance the care of patients with challenging fractures.

Dr. Seong-Eun Byun
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • fracture
  • fracture surgery
  • fracture healing
  • diagnosis
  • treatment

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Published Papers (3 papers)

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10 pages, 1803 KiB  
Article
Innovating Pelvic Fracture Surgery: Development and Evaluation of a New Surgical Table for Enhanced C-Arm Imaging and Operational Efficiency
by Yong-Cheol Yoon, Min Jun Kim, Ji Sub Lim and Hyung Keun Song
J. Clin. Med. 2025, 14(9), 3169; https://doi.org/10.3390/jcm14093169 - 3 May 2025
Viewed by 252
Abstract
Background: Pelvic fractures require precise reduction and stabilization, necessitating high-quality C-arm imaging and accurate patient positioning. Standard operating tables often obstruct optimal C-arm maneuverability. To address this, we developed a new auxiliary surgical table that integrates with existing tables and evaluated its clinical [...] Read more.
Background: Pelvic fractures require precise reduction and stabilization, necessitating high-quality C-arm imaging and accurate patient positioning. Standard operating tables often obstruct optimal C-arm maneuverability. To address this, we developed a new auxiliary surgical table that integrates with existing tables and evaluated its clinical utility compared to a specialized carbon surgical table. Methods: Between March 2018 and June 2023, we conducted a retrospective study involving 162 patients (97 men and 65 women; average age 45.7 years) who underwent percutaneous sacroiliac screw fixation for pelvic fractures. Ninety patients were treated using the newly developed table, and seventy-two patients were treated using the carbon table. The new table, measuring 200 cm in length, 50 cm in width, and 2 cm in thickness, was constructed from waterproof plywood and designed to be securely attached to existing operating tables. We compared surgical preparation times, economic costs, and intraoperative imaging feasibility between the two groups. Results: Use of the new table significantly reduced the surgical preparation time by an average of 21 min and saved approximately $43,000 in cost compared to the carbon table. Subjective assessments indicated no notable difference in intraoperative C-arm image quality between the two groups. The new table allowed free C-arm rotation by overcoming the mechanical limitations of conventional tables. Conclusions: The new auxiliary table demonstrated clinical feasibility and economic advantages without compromising intraoperative imaging quality, offering a practical and cost-effective alternative for pelvic fracture surgeries. Full article
(This article belongs to the Special Issue Accelerating Fracture Healing: Clinical Diagnosis and Treatment)
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11 pages, 1028 KiB  
Article
Comparative Analysis of Anterolateral and Posterior Approaches for Distal Humerus Shaft Fractures: A Multicenter Retrospective Study
by Yong-Cheol Yoon, Hyoung-Keun Oh, Hyung-Suh Kim and Joon-Woo Kim
J. Clin. Med. 2025, 14(9), 2890; https://doi.org/10.3390/jcm14092890 - 22 Apr 2025
Viewed by 304
Abstract
Background: Distal humeral shaft fractures (DHSFs) pose surgical challenges due to the proximity to the elbow joint, limited bone stock, and the risk of radial nerve injury. This study compared clinical and radiographic outcomes of anterolateral and posterior triceps-sparing approaches to determine [...] Read more.
Background: Distal humeral shaft fractures (DHSFs) pose surgical challenges due to the proximity to the elbow joint, limited bone stock, and the risk of radial nerve injury. This study compared clinical and radiographic outcomes of anterolateral and posterior triceps-sparing approaches to determine the most effective surgical strategy. Methods: This multicenter retrospective study included 75 patients who underwent surgery for a DHSF between 2015 and 2021, with a minimum one-year follow-up, a distal fragment ≥3 cm, and no preoperative radial nerve injury. Fifty patients underwent anterior plating via anterolateral approach, and twenty-five underwent posterior plating. Clinical and radiographic outcomes were evaluated. Results: Bone union was achieved in 74 patients (98.7%), with no significant difference between the groups (p = 0.21). The anterolateral approach resulted in a shorter operative time (116 ± 29.4 vs. 143 ± 31.4 min, p = 0.03). However, intraoperative blood loss (p = 0.36), Mayo Elbow Performance Score (p = 0.71), range of motion (p = 0.36), and complication rates (p = 0.21) were not significantly different. Two cases of transient radial nerve palsy occurred in the posterior group (p = 0.17), and four cases required implant removal due to discomfort (p = 0.18) in the anterolateral group. Conclusions: Both approaches effectively treat DHSFs with high union rates and comparable functional outcomes. However, the anterolateral approach significantly reduces operative time due to supine positioning, direct access, and avoiding radial nerve dissection. Posterior plating remains viable when stable anterior fixation is unachievable. Further studies should assess the long-term outcomes and factors influencing approach selection. Full article
(This article belongs to the Special Issue Accelerating Fracture Healing: Clinical Diagnosis and Treatment)
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Other

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14 pages, 5246 KiB  
Systematic Review
Risk Factors for Readmission Within 30 Days After Discharge Following Hip Fracture Surgery: A Systematic Review and Meta-Analysis
by Kyung-Joo Lee, Ji Wan Kim and Chul-Ho Kim
J. Clin. Med. 2025, 14(8), 2779; https://doi.org/10.3390/jcm14082779 - 17 Apr 2025
Viewed by 368
Abstract
Background/Objectives: Hip fractures in older patients frequently lead to early readmissions, which negatively impact patient outcomes and significantly increase healthcare costs. Identifying and understanding risk factors for 30-day readmission following hip fracture surgery is essential for improving patient management and optimizing healthcare resource [...] Read more.
Background/Objectives: Hip fractures in older patients frequently lead to early readmissions, which negatively impact patient outcomes and significantly increase healthcare costs. Identifying and understanding risk factors for 30-day readmission following hip fracture surgery is essential for improving patient management and optimizing healthcare resource utilization. Methods: A systematic literature search was conducted using PubMed, EMBASE, and the Cochrane Library databases up to 30 December 2024. Studies investigating potential risk factors for 30-day readmission following hip fracture surgery were included. The risk factors were meta-analytically pooled, and odds ratios (ORs) were calculated using a random-effects model. Results: Twelve studies comprising 128,053 patients were included. Pooled analyses revealed significant associations between higher readmission rates and factors such as male sex (OR = 1.45; 95% CI, 1.27–1.65), hip arthroplasty surgery (OR = 1.36; 95% CI, 1.03–1.80), advanced age (OR, 1.22; 95% CI 1.00–1.49), high American Society of Anesthesiologists (ASA) Physical Status Classification System class (OR, 2.22; 95% CI, 1.28–3.85), and high Charlson comorbidity index (OR, 1.67; 95% CI, 1.36–2.05). Additionally, the most frequently reported comorbidities associated with higher readmission risks were diabetes mellitus and congestive heart failure, with ORs of 1.63 and 1.57, respectively. Conclusions: Male sex, advanced age, higher ASA scores, and greater preoperative comorbidity burdens significantly increase the risk of 30-day readmission following hip fracture surgery. Effective risk stratification and targeted perioperative management strategies addressing these identified factors may reduce early readmission rates and enhance postoperative patient outcomes. Full article
(This article belongs to the Special Issue Accelerating Fracture Healing: Clinical Diagnosis and Treatment)
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