Clinical Advances in Cardiac Imaging

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 20 July 2025 | Viewed by 2525

Special Issue Editor

Special Issue Information

Dear Colleagues,

I would like to invite you to contribute to the upcoming Special Issue, “Clinical Advances in Cardiac Imaging”. The aim of this Special Issue is to explore new technological developments in the field of modern cardiac imaging, encompassing non-invasive imaging methods such as echocardiography, MRI, CT, SPECT, and PET. All types of studies, including original articles and reviews, are welcome. This Special Issue will focus mainly on improvements in the early detection, faster diagnosis, and better management of cardiovascular diseases. Core challenges include the need for improvement in diagnostic accuracy, the limitation of side effects, the time and/or costs of testing, new applications for the integration of imaging modalities, and improving accuracy in the interpretation of imaging results.

The scope of this Special Issue covers a broad range of topics, including advancements in imaging techniques, multimodal imaging, the integration of artificial intelligence into image analysis, and new clinical applications in various cardiovascular diseases. Interdisciplinary studies combining expertise from various fields of medicine, such as sports cardiology, rheumatology, infectious diseases, or oncology, are also welcome.

The aim of this Special Issue is to encourage collaboration among researchers, clinicians, and technological companies, to encourage innovation and enhance practical applications.

Prof. Dr. Łukasz A. Małek
Guest Editor

Manuscript Submission Information

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Keywords

  • non-invasive imaging
  • heart
  • vessels
  • application
  • diagnosis
  • technique

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Published Papers (2 papers)

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Research

11 pages, 2028 KiB  
Article
Role of Multimodality Imaging in Cardiac Sarcoidosis: A Retrospective Single-Center Experience
by Vincent A. Torelli, Sanjay Sivalokanathan, Alexander Silverman, Syed Zaidi, Usman Saeedullah, Komail Jafri, James Choi, Luka Katic, Serdar Farhan and Ashish Correa
J. Clin. Med. 2024, 13(23), 7335; https://doi.org/10.3390/jcm13237335 - 2 Dec 2024
Cited by 1 | Viewed by 948
Abstract
Background/Objectives: Cardiac sarcoidosis (CS) is a rare entity characterized by granulomatous infiltration of the myocardium, which can lead to myocardial fibrosis, conduction abnormalities, and the development of heart failure, thereby elevating the risk of sudden cardiac death (SCD). While endomyocardial biopsy (EMBx) is [...] Read more.
Background/Objectives: Cardiac sarcoidosis (CS) is a rare entity characterized by granulomatous infiltration of the myocardium, which can lead to myocardial fibrosis, conduction abnormalities, and the development of heart failure, thereby elevating the risk of sudden cardiac death (SCD). While endomyocardial biopsy (EMBx) is regarded as the gold standard for diagnosis, its low sensitivity and inherent procedural risks may limit its practical application. Methods: This study retrospectively explored the role of advanced imaging modalities, specifically cardiovascular magnetic resonance imaging (CMR) and fluorodeoxyglucose positron emission tomography (FDG-PET), in the diagnosis and management of CS within a single center. In this retrospective study, we aimed to assess the utility of advanced imaging modalities in the clinical diagnosis of CS and the monitoring of treatment. Results: A total of 92 patients were identified as having cardiac sarcoidosis, with males constituting 66.3% of the sample and a mean age of 62 years (±11.9). Among these patients, 80 (87%) underwent FDG-PET. Here, the basal inferolateral segment was the most frequently observed segment of the heart with FDG uptake. A total of 77 patients (84%) underwent CMR, with 51 demonstrating late gadolinium enhancement (LGE). The basal inferolateral segment exhibited the highest frequency of LGE (26%). Logistic regression analysis indicated that patients presenting with a combination of LGE, FDG uptake on PET, and a “mismatch pattern” faced a two-fold increase in the risk of experiencing major adverse cardiac events (odds ratio = 2.311, p = 0.077). Conclusions: This study underscores the importance of multimodality imaging as a non-invasive alternative for CS diagnosis and management, reducing reliance on EMBx. Full article
(This article belongs to the Special Issue Clinical Advances in Cardiac Imaging)
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10 pages, 921 KiB  
Article
Older Age as a Predictor of Ongoing Active Changes in Follow-Up Cardiac Magnetic Resonance in Children with Acute Myocarditis
by Łukasz A. Małek, Anna Gwiazda and Marzena Barczuk-Falęcka
J. Clin. Med. 2024, 13(21), 6498; https://doi.org/10.3390/jcm13216498 - 30 Oct 2024
Viewed by 948
Abstract
Background/Objectives: Cardiac magnetic resonance (CMR) is used to diagnose and monitor the course of acute myocarditis in adults and children. This study aimed to assess the frequency of persistent inflammation at follow-up CMR and to look for predictors of ongoing active changes [...] Read more.
Background/Objectives: Cardiac magnetic resonance (CMR) is used to diagnose and monitor the course of acute myocarditis in adults and children. This study aimed to assess the frequency of persistent inflammation at follow-up CMR and to look for predictors of ongoing active changes in CMR in children with myocarditis. Methods: This retrospective study included 31 children (median age 15 years, 68% male) with clinically and CMR-diagnosed acute myocarditis who underwent baseline and follow-up CMR at a median of 6 months. Old and new Lake Louise criteria were compared. Results: A complete resolution of changes was observed in four patients (13%) at follow-up, according to both criteria. Seven patients (23%) presented ongoing active changes, and twenty (64%) showed a persistent scar according to the old Lake Louise criteria. When the new Lake Louise criteria were used, an additional two patients (6%) were found to have persistent active changes instead of a persistent scar. Patients with persistent inflammation (nine patients, 29%) were older than those who showed recovery. None of the patients below 14 years of age presented active changes on their follow-up CMR and all the patients who showed inflammation were between 14 and 17 years old. Conclusions: Pediatric myocarditis can lead to persistent active changes in CMR beyond a 6-month follow-up in over a fifth of patients. The application of new Lake Louise criteria further increases that number compared to the old criteria. The only predictor of persistent inflammatory changes in CMR is older age. Full article
(This article belongs to the Special Issue Clinical Advances in Cardiac Imaging)
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