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Clinical Advances in Cardiac Imaging
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Clinical Advances in Cardiac Imaging

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 20 July 2025 | Viewed by 2611

Special Issue Editor

Prof. Dr. Łukasz A. Małek

E-Mail Website1 Website2
Guest Editor
Faculty of Rehabilitation, University of Physical Education, Marymoncka 34, 00-968 Warsaw, Poland
Interests: cardiac magnetic resonance; myocardial infarction; cardiovascular diseases; cardiology; sports cardiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

I would like to invite you to contribute to the upcoming Special Issue, “Clinical Advances in Cardiac Imaging”. The aim of this Special Issue is to explore new technological developments in the field of modern cardiac imaging, encompassing non-invasive imaging methods such as echocardiography, MRI, CT, SPECT, and PET. All types of studies, including original articles and reviews, are welcome. This Special Issue will focus mainly on improvements in the early detection, faster diagnosis, and better management of cardiovascular diseases. Core challenges include the need for improvement in diagnostic accuracy, the limitation of side effects, the time and/or costs of testing, new applications for the integration of imaging modalities, and improving accuracy in the interpretation of imaging results.

The scope of this Special Issue covers a broad range of topics, including advancements in imaging techniques, multimodal imaging, the integration of artificial intelligence into image analysis, and new clinical applications in various cardiovascular diseases. Interdisciplinary studies combining expertise from various fields of medicine, such as sports cardiology, rheumatology, infectious diseases, or oncology, are also welcome.

The aim of this Special Issue is to encourage collaboration among researchers, clinicians, and technological companies, to encourage innovation and enhance practical applications.

Prof. Dr. Łukasz A. Małek
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • non-invasive imaging
  • heart
  • vessels
  • application
  • diagnosis
  • technique

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Published Papers (3 papers)

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Research

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11 pages, 2028 KiB  
Article
Role of Multimodality Imaging in Cardiac Sarcoidosis: A Retrospective Single-Center Experience
by Vincent A. Torelli, Sanjay Sivalokanathan, Alexander Silverman, Syed Zaidi, Usman Saeedullah, Komail Jafri, James Choi, Luka Katic, Serdar Farhan and Ashish Correa
J. Clin. Med. 2024, 13(23), 7335; https://doi.org/10.3390/jcm13237335 - 2 Dec 2024
Cited by 1 | Viewed by 981
Abstract
Background/Objectives: Cardiac sarcoidosis (CS) is a rare entity characterized by granulomatous infiltration of the myocardium, which can lead to myocardial fibrosis, conduction abnormalities, and the development of heart failure, thereby elevating the risk of sudden cardiac death (SCD). While endomyocardial biopsy (EMBx) is [...] Read more.
Background/Objectives: Cardiac sarcoidosis (CS) is a rare entity characterized by granulomatous infiltration of the myocardium, which can lead to myocardial fibrosis, conduction abnormalities, and the development of heart failure, thereby elevating the risk of sudden cardiac death (SCD). While endomyocardial biopsy (EMBx) is regarded as the gold standard for diagnosis, its low sensitivity and inherent procedural risks may limit its practical application. Methods: This study retrospectively explored the role of advanced imaging modalities, specifically cardiovascular magnetic resonance imaging (CMR) and fluorodeoxyglucose positron emission tomography (FDG-PET), in the diagnosis and management of CS within a single center. In this retrospective study, we aimed to assess the utility of advanced imaging modalities in the clinical diagnosis of CS and the monitoring of treatment. Results: A total of 92 patients were identified as having cardiac sarcoidosis, with males constituting 66.3% of the sample and a mean age of 62 years (±11.9). Among these patients, 80 (87%) underwent FDG-PET. Here, the basal inferolateral segment was the most frequently observed segment of the heart with FDG uptake. A total of 77 patients (84%) underwent CMR, with 51 demonstrating late gadolinium enhancement (LGE). The basal inferolateral segment exhibited the highest frequency of LGE (26%). Logistic regression analysis indicated that patients presenting with a combination of LGE, FDG uptake on PET, and a “mismatch pattern” faced a two-fold increase in the risk of experiencing major adverse cardiac events (odds ratio = 2.311, p = 0.077). Conclusions: This study underscores the importance of multimodality imaging as a non-invasive alternative for CS diagnosis and management, reducing reliance on EMBx. Full article
(This article belongs to the Special Issue Clinical Advances in Cardiac Imaging)
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10 pages, 921 KiB  
Article
Older Age as a Predictor of Ongoing Active Changes in Follow-Up Cardiac Magnetic Resonance in Children with Acute Myocarditis
by Łukasz A. Małek, Anna Gwiazda and Marzena Barczuk-Falęcka
J. Clin. Med. 2024, 13(21), 6498; https://doi.org/10.3390/jcm13216498 - 30 Oct 2024
Viewed by 969
Abstract
Background/Objectives: Cardiac magnetic resonance (CMR) is used to diagnose and monitor the course of acute myocarditis in adults and children. This study aimed to assess the frequency of persistent inflammation at follow-up CMR and to look for predictors of ongoing active changes [...] Read more.
Background/Objectives: Cardiac magnetic resonance (CMR) is used to diagnose and monitor the course of acute myocarditis in adults and children. This study aimed to assess the frequency of persistent inflammation at follow-up CMR and to look for predictors of ongoing active changes in CMR in children with myocarditis. Methods: This retrospective study included 31 children (median age 15 years, 68% male) with clinically and CMR-diagnosed acute myocarditis who underwent baseline and follow-up CMR at a median of 6 months. Old and new Lake Louise criteria were compared. Results: A complete resolution of changes was observed in four patients (13%) at follow-up, according to both criteria. Seven patients (23%) presented ongoing active changes, and twenty (64%) showed a persistent scar according to the old Lake Louise criteria. When the new Lake Louise criteria were used, an additional two patients (6%) were found to have persistent active changes instead of a persistent scar. Patients with persistent inflammation (nine patients, 29%) were older than those who showed recovery. None of the patients below 14 years of age presented active changes on their follow-up CMR and all the patients who showed inflammation were between 14 and 17 years old. Conclusions: Pediatric myocarditis can lead to persistent active changes in CMR beyond a 6-month follow-up in over a fifth of patients. The application of new Lake Louise criteria further increases that number compared to the old criteria. The only predictor of persistent inflammatory changes in CMR is older age. Full article
(This article belongs to the Special Issue Clinical Advances in Cardiac Imaging)
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Review

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35 pages, 4927 KiB  
Review
The Role of Cardiovascular Magnetic Resonance Imaging in Athletic Individuals—A Narrative Review
by Neil Grech and Mark Abela
J. Clin. Med. 2025, 14(10), 3576; https://doi.org/10.3390/jcm14103576 - 20 May 2025
Abstract
Cardiovascular magnetic resonance imaging (MRI) is an advanced cardiac imaging modality that is often required when evaluating athletic individuals. Unrestricted imaging planes, excellent spatial resolution, and a lack of ionising radiation are some of the benefits of this modality. Cardiac MRI has been [...] Read more.
Cardiovascular magnetic resonance imaging (MRI) is an advanced cardiac imaging modality that is often required when evaluating athletic individuals. Unrestricted imaging planes, excellent spatial resolution, and a lack of ionising radiation are some of the benefits of this modality. Cardiac MRI has been established as the gold standard imaging modality for morphological assessment, volumetric analysis, and tissue characterisation. Cardiac MRI without any doubt is an excellent diagnostic tool when evaluating athletes with symptoms or those individuals exhibiting equivocal findings at screening. It is also useful for athletes who fall within the grey zone and is especially important among athletes with a suspected or confirmed diagnosis. Cardiac MRI plays a strategic role when adopting a shared decision-making model in athletes with heart disease, tailoring and personalising medical care to the condition and the athlete’s wishes. The aim of this review is to provide a comprehensive yet practical overview of the role of cardiac MRI when evaluating athletes in clinic. Full article
(This article belongs to the Special Issue Clinical Advances in Cardiac Imaging)
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