Aortic Aneurysms: Recent Advances in Diagnosis and Treatment

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: 23 September 2025 | Viewed by 1866

Special Issue Editors


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Guest Editor
Department of Vascular Surgery, St. Franziskus-Hospital Münster, Munster, Germany
Interests: aorta; fenestrated and/or branched endovascular repair (F/BEVAR); endovascular treatment; intravascular ultra-sound (IVUS); bridging stent graft; dissection, thoracoabdominal aneurysm; in situ fenestration

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Guest Editor
Section of Vascular Surgery, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
Interests: aorta; fenestrated and/or branched endovascular repair (F/BEVAR); endovascular treatment; intravascular ultra-sound (IVUS); bridging stent graft; dissection; thoracoabdominal aneurysm

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Guest Editor
Clinic of Vascular and Endovascular Surgery, Department of Vascular and Endovascular Surgery, University of Padova Medical School, Padova, Italy
Interests: aorta; fenestrated and/or branched endovascular repair (F/BEVAR); endovascular treatment; thoracoabdominal an-eurysm

Special Issue Information

Dear Colleagues,

Thoraco-abdominal aortic aneurysms (TAAAs) are associated with high morbidity and mortality if not treated in a timely and appropriate manner. Endovascular treatment of TAAAs is now considered the gold standard due to its short operative time, reduced invasiveness and low mortality.

However, several issues are still under debate, such as the risk of spinal cord ischemia, the choice of appropriate grafts and long-term outcomes, which require new robust data on new materials to be added to the literature.

In particular, the use of physician-modified grafts to address complex aortic anatomies not amenable to off-the-shelf treatment needs to be investigated. In addition, improving standards of adjunctive medical treatment and perioperative management is key to achieving better outcomes and standardizing treatment.

This Special Issue focuses on current advanced and new treatment options for thoraco-abdominal aortic aneurysms.

Therefore, we welcome the submissions of innovative, original research and in-depth review articles dealing with pioneering management and/or treatment techniques for TAAAs.

Dr. Marco Virgilio Usai
Dr. Giuseppe Asciutto
Dr. Michele Piazza
Guest Editors

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Keywords

  • aortic aneurysms
  • abdominal aortic
  • thoraco-abdominal aortic aneurysms (TAAAs)
  • complex aortic anatomies
  • endovascular abdominal aortic aneurysm repair (EVAR)
  • endovascular thoracic aortic aneurysm repair (TEVAR)
  • endovascular treatment

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Published Papers (2 papers)

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Research

12 pages, 904 KiB  
Article
Serum Creatinine Level in Relation to Intraluminal Thrombus and Abdominal Aortic Aneurysm Size
by Louise Røtzler Holm, Jonas Peter Eiberg, Qasam M. Ghulam, Alexander Hakon Zielinski, Rebecca Andrea Conradsen Skov and on behalf of the COACH Research Collaborative
J. Clin. Med. 2025, 14(4), 1258; https://doi.org/10.3390/jcm14041258 - 14 Feb 2025
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Abstract
Objectives: Abdominal aortic aneurysm (AAA) diameter is the primary predictor of AAA rupture. However, smaller aneurysms do rupture, and other parameters are required for a more nuanced risk stratification. Reduced renal function is associated with increased cardiovascular risk and thrombosis, but the [...] Read more.
Objectives: Abdominal aortic aneurysm (AAA) diameter is the primary predictor of AAA rupture. However, smaller aneurysms do rupture, and other parameters are required for a more nuanced risk stratification. Reduced renal function is associated with increased cardiovascular risk and thrombosis, but the impact of renal function on ILT and AAA size remains unknown. This study aimed to investigate the association between creatinine level and volume of ILT and AAA. Methods: In a cross-sectional study, 184 patients with AAA under ultrasound surveillance were included. ILT volume and thickness, and AAA volume and diameter, were measured using three-dimensional contrast-enhanced ultrasound. ILT and AAA measures were compared with creatinine levels. Results: No associations were found between creatinine level and ILT or AAA volume (p = 0.18 and p = 0.41). There were no differences in ILT volume between patients with normal and elevated creatinine levels, when adjusting for AAA size and comorbidities (p = 0.06 and p = 0.54). A positive association was found between ILT volume and AAA volume (p < 0.001). Creatinine level did not influence this association (p = 0.06). Conclusions: In this study, creatinine level did not seem associated with ILT or AAA volume. Longitudinal studies are required to elucidate associations between renal function, clinical outcomes, and ILT and AAA development. Full article
(This article belongs to the Special Issue Aortic Aneurysms: Recent Advances in Diagnosis and Treatment)
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8 pages, 1054 KiB  
Article
Preoperative and Postoperative Arterial Adaptation in Patients with Acute Aortic Dissection
by Marian Burysz, Mariusz Kowalewski, Natalia Piekuś-Słomka, Jerzy Walocha, Jarosław Zawiliński, Radoslaw Litwinowicz and Jakub Batko
J. Clin. Med. 2024, 13(23), 7362; https://doi.org/10.3390/jcm13237362 - 3 Dec 2024
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Abstract
Background: Spinal cord ischemia is one of the most serious complications after an aortic repair. To date, there is no evidence for arterial changes during an aortic dissection or for the observation of such arteries after an aortic repair. The aim of this [...] Read more.
Background: Spinal cord ischemia is one of the most serious complications after an aortic repair. To date, there is no evidence for arterial changes during an aortic dissection or for the observation of such arteries after an aortic repair. The aim of this study was to compare spinal-cord-supplying arteries in patients with an acute aortic dissection, preoperatively and postoperatively, with patients without an acute aortic dissection. Methods: Preoperative and postoperative contrast-enhanced computed tomography scans of 25 patients who had undergone the frozen elephant trunk procedure to treat an aortic dissection and 25 patients who qualified for a transcatheter aortic valve replacement without an acute aortic dissection and atherosclerosis of the analyzed vessels, treated as a control group, were reconstructed and retrospectively analyzed with the detailed medical data of the patients. The aortic branches with the ability to supply blood to the spinal cord as described in the literature were further analyzed. Results: The preoperative arterial diameters of the left internal thoracic artery, the left musculophrenic artery, and the left and right supreme intercostal arteries were significantly larger compared to the postoperative measurements. In addition, the preoperative measurements of the diameters of the left vertebral artery, right internal thoracic artery, left lateral thoracic artery, and left common iliac artery were significantly larger than in the control group. Conclusions: The internal thoracic arteries and supreme intercostal arteries may play a crucial role in providing additional blood supply to the spinal cord. Full article
(This article belongs to the Special Issue Aortic Aneurysms: Recent Advances in Diagnosis and Treatment)
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