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23 March 2026
Journal of Clinical Medicine | Notable Perspectives Papers


We are delighted to share Notable Perspectives Papers from the Journal of Clinical Medicine (JCM, ISSN: 2077-0383). These selected papers have drawn significant attention and cover our 12 sections, including but not limited to respiratory medicine, nephrology & urology, and nuclear medicine & radiology. We sincerely thank our Editorial Board Members for their valuable contributions, and we invite researchers from a wide range of clinical and research backgrounds to read these articles.

1. “Shaping the Future of Healthcare: Ethical Clinical Challenges and Pathways to Trustworthy AI”
by Polat Goktas and Andrzej Grzybowski
J. Clin. Med. 2025, 14(5), 1605; https://doi.org/10.3390/jcm14051605
Full text available online: https://www.mdpi.com/2077-0383/14/5/1605

2. “Next-Generation Immunotherapy: Advancing Clinical Applications in Cancer Treatment”
by Pankaj Garg, Siddhika Pareek, Prakash Kulkarni, David Horne, Ravi Salgia and Sharad S. Singhal
J. Clin. Med. 2024, 13(21), 6537; https://doi.org/10.3390/jcm13216537
Full text available online: https://www.mdpi.com/2077-0383/13/21/6537

3. “Advancing Clinical Practice: The Potential of Multimodal Technology in Modern Medicine”
by Yaara Artsi, Vera Sorin, Benjamin S. Glicksberg, Girish N. Nadkarni and Eyal Klang
J. Clin. Med. 2024, 13(20), 6246; https://doi.org/10.3390/jcm13206246
Full text available online: https://www.mdpi.com/2077-0383/13/20/6246

4. “New Horizons of Artificial Intelligence in Medicine and Surgery”
by Valerii Luțenco, George Țocu, Mădălin Guliciuc, Monica Moraru, Iuliana Laura Candussi, Marius Dănilă, Verginia Luțenco, Florentin Dimofte, Oana Mariana Mihailov and Raul Mihailov
J. Clin. Med. 2024, 13(9), 2532; https://doi.org/10.3390/jcm13092532
Full text available online: https://www.mdpi.com/2077-0383/13/9/2532

5. “Application of Artificial Intelligence in Otology: Past, Present, and Future”
by Hajime Koyama, Akinori Kashio and Tatsuya Yamasoba
J. Clin. Med. 2024, 13(24), 7577; https://doi.org/10.3390/jcm13247577
Full text available online: https://www.mdpi.com/2077-0383/13/24/7577

6. “The Role of Immunotherapy in MMR-Deficient Endometrial Carcinoma: State of the Art and Future Perspectives”
by Matteo Marchetti, Jacopo Ferrari, Tommaso Vezzaro, Laura Masatti, Giulia Tasca, Tiziano Maggino, Roberto Tozzi, Carlo Saccardi, Marco Noventa and Giulia Spagnol
J. Clin. Med. 2024, 13(23), 7041; https://doi.org/10.3390/jcm13237041
Full text available online: https://www.mdpi.com/2077-0383/13/23/7041

7. “Kidney Damage in Pediatric Obesity: Insights from an Emerging Perspective”
by Gianmario Forcina, Margherita Luciano, Vittoria Frattolillo, Simona Mori, Noemi Monaco, Stefano Guarino, Pierluigi Marzuillo, Emanuele Miraglia del Giudice and Anna Di Sessa
J. Clin. Med. 2024, 13(23), 7025; https://doi.org/10.3390/jcm13237025
Full text available online: https://www.mdpi.com/2077-0383/13/23/7025

8. “Hyperreflective Retinal Foci (HRF): Definition and Role of an Invaluable OCT Sign”
by Luisa Frizziero, Giulia Midena, Luca Danieli, Tommaso Torresin, Antonio Perfetto, Raffaele Parrozzani, Elisabetta Pilotto and Edoardo Midena
J. Clin. Med. 2025, 14(9), 3021; https://doi.org/10.3390/jcm14093021
Full text available online: https://www.mdpi.com/2077-0383/14/9/3021

9. “Nanoengineering Solutions for Cancer Therapy: Bridging the Gap between Clinical Practice and Translational Research”
by Pankaj Garg, Siddhika Pareek, Prakash Kulkarni, Ravi Salgia and Sharad S. Singhal
J. Clin. Med. 2024, 13(12), 3466; https://doi.org/10.3390/jcm13123466
Full text available online: https://www.mdpi.com/2077-0383/13/12/3466

10. “Controlled Mechanical Ventilation in Critically Ill Patients and the Potential Role of Venous Bagging in Acute Kidney Injury”
by Mark E. Seubert and Marco Goeijenbier
J. Clin. Med. 2024, 13(5), 1504; https://doi.org/10.3390/jcm13051504
Full text available online: https://www.mdpi.com/2077-0383/13/5/1504

11. “From Awake to Minimalist Spontaneous Ventilation Thoracoscopic Lung Surgery: An Ongoing Journey”
by Eugenio Pompeo
J. Clin. Med. 2025, 14(7), 2475; https://doi.org/10.3390/jcm14072475
Full text available online: https://www.mdpi.com/2077-0383/14/7/2475

12. “Combining Advanced Targeted Therapy in Inflammatory Bowel Disease: Current Practice and Future Directions”
by Alice De Bernardi, Cristina Bezzio, Michele Puricelli, Daniela Gilardi and Simone Saibeni
J. Clin. Med. 2025, 14(2), 590; https://doi.org/10.3390/jcm14020590
Full text available online: https://www.mdpi.com/2077-0383/14/2/590

13. “Balancing Ethics and Innovation: Can Artificial Intelligence Safely Transform Emergency Surgery? A Narrative Perspective”
by Belinda De Simone, Genevieve Deeken and Fausto Catena
J. Clin. Med. 2025, 14(9), 3111; https://doi.org/10.3390/jcm14093111
Full text available online: https://www.mdpi.com/2077-0383/14/9/3111

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