Recent Studies on Resource Insects

A special issue of Insects (ISSN 2075-4450).

Deadline for manuscript submissions: 10 February 2026 | Viewed by 530

Special Issue Editors


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Guest Editor
Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing 100093, China
Interests: honeybee; omics; honeybee product; beekeeping; honeybee health
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Institute of Plant Protection, Sichuan Academy of Agricultural Science, Chengdu 100093, China
Interests: crop diseases and pests; plant pathology; molecular biology

Special Issue Information

Dear Colleagues,

Insects, as a renewable natural resource, hold significant potential for diverse applications across various industries. In recent years, they have become a key focus of scientific research and industrial development. Insect products and bodies serve as valuable industrial raw materials and biomaterials, with a wide range of uses. Rich in proteins and amino acids, they are not only suitable for human consumption but also offer high nutritional value as animal feed. In the agricultural and forestry sectors, beneficial insects play a crucial role in sustainable pest control, contributing to ecological pest management and supporting environmental protection efforts. Moreover, the study of insect structures and functions has driven advancements in biomimicry, leading to the development of innovative high-tech products with applications in medicine, military, and materials science.

This Special Issue seeks to gather the most recent advances in resource insect research. We invite experts and researchers to submit their work and contribute to the growing body of knowledge on how insects can be leveraged for a wide range of scientific and industrial purposes.

Prof. Dr. Yue Hao
Prof. Dr. Weili Cai
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Insects is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • resource insects
  • beneficial insects
  • insect products
  • biomimicry
  • bioengineering

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Published Papers (1 paper)

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Research

21 pages, 2184 KiB  
Article
Dissecting the Molecular Mechanism of 10-HDA Biosynthesis: Role of Acyl-CoA Delta(11) Desaturase and Transcriptional Regulators in Honeybee Mandibular Glands
by Yunchang Li, Xiaojing Zhang, Zhenyu Xia and Yue Hao
Insects 2025, 16(6), 563; https://doi.org/10.3390/insects16060563 - 26 May 2025
Viewed by 339
Abstract
10-Hydroxy-2-decenoic acid (10-HDA), a major fatty acid (FA) component of royal jelly, is synthesized in the mandibular glands (MGs) of worker honeybees. Despite its well-documented nutritional and therapeutic significance, the biosynthetic pathway and regulatory mechanisms of 10-HDA production remain largely unresolved. In this [...] Read more.
10-Hydroxy-2-decenoic acid (10-HDA), a major fatty acid (FA) component of royal jelly, is synthesized in the mandibular glands (MGs) of worker honeybees. Despite its well-documented nutritional and therapeutic significance, the biosynthetic pathway and regulatory mechanisms of 10-HDA production remain largely unresolved. In this study, the molecular basis of 10-HDA biosynthesis and regulation in the MGs of newly emerged bees (NEBs), nurse bees (NBs), and forager bees (FBs) were investigated using RNA sequencing and weighted gene co-expression network analysis (WGCNA). A five-step biosynthetic pathway for 10-HDA was proposed, and cross-species analysis of Apis mellifera and A. cerana revealed the conserved expression patterns of 15 key enzymes involved. Functional validation via RNA interference (RNAi) demonstrated that knockdown of acyl-CoA Delta(11) desaturase (d11ds, LOC551527), a key enzyme in FA desaturation, led to a 50% reduction in 10-HDA levels. Protein–protein interaction (PPI) network analysis further identified transcriptional regulators Kay and Drep-2 as potential modulators of 10-HDA metabolism. This study provides the first comprehensive mechanistic model of 10-HDA biosynthesis in honeybee MGs and highlights the labor-specific regulation of FA metabolism. These findings offer promising genetic targets for improving the royal jelly quality through genetic technology. Full article
(This article belongs to the Special Issue Recent Studies on Resource Insects)
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