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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Zebrafish Model for Neurological Research
edited by
submission deadline 30 Nov 2025 | Viewed by 14 | Submission Open
Keywords: zebrafish  ; Danio rerio  ; brain  ; nervous system
(This special issue belongs to the Section Molecular Neurobiology)
Advances in Targeted Therapies and Immunometabolic Pathways in Cancer
edited by Medhi Wangpaichitr
submission deadline 30 Nov 2025 | Viewed by 12 | Submission Open
Keywords: immunotherapy; targeted therapy; tumor metabolism pathway; tumor microenvironment; immune checkpoint blockade; immune evasion; glucose/amino acids/lipid metabolism
(This special issue belongs to the Section Molecular Immunology)
Molecular Perspectives in Tissue Engineering and Regenerative Medicine
edited by
submission deadline 30 Nov 2025 | Viewed by 11 | Submission Open
Keywords: 3D scaffolds; personalized regenerative therapies; tissue engineering; stem cells; bone regeneration; regenerative biomarkers; cell–scaffold interactions; nanomaterials
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanisms and Treatment of Retinal Diseases
edited by and
submission deadline 30 Nov 2025 | Viewed by 3 | Submission Open
Keywords: nutritional supplementations; high myopia; optometry; cell therapy; drug delivery; age-related macular degeneration; glaucoma; retinal degeneration; choroidal thinning; scleral remodeling; light therapy; digital healthcare; prematurity of retionopathy; carotid artery occlusion; retinal ischemia; inflammation; eye drop
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Rheumatoid Arthritis: From Molecular Mechanism to Emerging Therapeutic Target
edited by Elisa Gremese and Costantino Pitzalis
submission deadline 30 Nov 2025 | Viewed by 1 | Submission Open
Keywords: rheumatoid arthritis; molecular mechanisms; emerging therapeutic targets; precision medicine; synovial tissue
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Current Landscape of Microglia-Glioma Research: From Basic Science to Therapeutic Potential submission deadline 1 Dec 2025 | Viewed by 299 | Submission Open
Keywords: microglia; glioma; tumor associated macrophages; immunosuppression; epigenetics
(This special issue belongs to the Section Molecular Neurobiology)
Gene Editing for Cereal Crops
edited by
submission deadline 1 Dec 2025 | Viewed by 64 | Submission Open
Keywords: gene-editing techniques; novel germplasm; quality; nutrition; agronomic traits
(This special issue belongs to the Section Molecular Plant Sciences)
Long-COVID and Its Complications
edited by
submission deadline 4 Dec 2025 | 4 articles | Viewed by 20570 | Submission Open
Keywords: acquired immune deficiency; auto-immunity; blood– brain barrier dysfunction; complication; COVID-19; gut microbiome; hypothalamic– pituitary– adrenal axis; immune dysfunction; long COVID; multisystem dysfunction; neurological complications; SARS-CoV-2; systemic inflammation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Biology of Oral Cancer
edited by Rafał Pęksa
submission deadline 10 Dec 2025 | Viewed by 52 | Submission Open
Keywords: oral cancer; molecular mechanisms; biomarkers; tumor microenvironment; therapy resistance; precision medicine; carcinogenesis; oral squamous cell carcinoma; epigenetics; microbiome; immunotherapy; liquid biopsy
(This special issue belongs to the Section Molecular Oncology)
Plant Responses to Biotic and Abiotic Stresses
edited by
submission deadline 20 Dec 2025 | 13 articles | Viewed by 10557 | Submission Open
Keywords: plant enzymes and metabolites; abiotic stress; stress response; phytohormones; secondary metabolism; gene regulation network; developmental and environmental adaptation; microbial interactions; biotic stress; pathogen response
(This special issue belongs to the Section Molecular Plant Sciences)
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