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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Role of Natural Products in Treating Human Diseases
edited by Luís R. Silva
submission deadline 30 Sep 2025 | Viewed by 479 | Submission Open
Keywords: natural products; phytochemicals; biological potential; pharmacological activity; health promoters; chronic diseases
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Osteoblast Differentiation in Human Health and Disease
edited by Younho Han
submission deadline 30 Sep 2025 | 1 articles | Viewed by 478 | Submission Open
Keywords: osteoblast differentiation; bone remodeling; mesenchymal stem cells; skeletal diseases; osteogenesis; bone mineralization; osteoporosis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Optical Materials: Molecular Advances of Their Synthesis, Properties and Medical Applications submission deadline 30 Sep 2025 | Viewed by 471 | Submission Open
Keywords: optical materials; luminescence; luminescence thermometry; laser materials; phosphors; biocompatible optical materials; optical imaging; fluorescent nanoparticles; rare-earth ion-doped nanomaterials; hard and soft tissue engineering; laser imaging systems
(This special issue belongs to the Section Materials Science)
Bioactive Compound Delivery Systems and Microbiome Interactions submission deadline 30 Sep 2025 | Viewed by 388 | Submission Open
Keywords: bioactive compounds; delivery systems; gut microbiome; personalized nutrition; bioavailability; encapsulation technologies; microbiome– bioactive interactions; targeted delivery; precision nutrition; synergistic interactions
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Mechanism of VCP/p97 in Health and Diseases
edited by
submission deadline 30 Sep 2025 | Viewed by 374 | Submission Open
Keywords: AAA ATPase; VCP/p97/cdc48/TER ATPase; AAA ATPase; protein unfolding; protein degradation; protein quality control; ERAD; mitochondria-associated degradation; lysosome degradation; ribosome-associated degradation; membrane fusion and trafficking; ubiquitin; TDP43; inclusion body myopathy (IBM); paget disease (PD); frontotemporal dementia (FD); MSP1; amyotrophic lateral sclerosis (ALS); charcot-marie-tooth disease 2Y; Parkinson’ s disease; intellectual development disabilities (IDDs); lysosomal diseases; tauopathies
(This special issue belongs to the Section Molecular Biology)
Current Trends in Redox Physiology Research
edited by Fotios Tekos
submission deadline 30 Sep 2025 | Viewed by 342 | Submission Open
Keywords: redox biology; oxidative stress; antioxidant mechanisms; redox signaling; cellular homeostasis; inflammation and redox; nutritional redox modulation; environmental toxicology and redox; mitochondrial dysfunction; oxidative stress biomarkers
(This special issue belongs to the Section Biochemistry)
X-Linked Disorders: Epigenetic and Environmental Modulation of Phenotypes
edited by Yoram Chaiter and
submission deadline 30 Sep 2025 | Viewed by 325 | Submission Open
Keywords: X-linked disorders; epigenetics; environmental factors; gene expression; clinical manifestations
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Insights into the Precision Medicine on Neoplastic Diseases: Challenges, Perspectives and Opportunities
edited by
submission deadline 30 Sep 2025 | Viewed by 322 | Submission Open
Keywords: cancer; molecular biology; precision medicine; targeted therapy
(This special issue belongs to the Section Molecular Oncology)
New Advances in Platelet Biology and Functions: 3rd Edition
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 272 | Submission Open
Keywords: platelet microparticles; thrombosis; inflammation; oxidative stress; antiplatelet drug; signal transduction; immunity; tumor growth
(This special issue belongs to the Section Molecular Biology)
Lipid Emulsion and Other Treatment in Drug Toxicity
edited by
submission deadline 30 Sep 2025 | Viewed by 271 | Submission Open
Keywords: lipid emulsions; toxicity; toxic drug; anesthetic drug
(This special issue belongs to the Section Molecular Pharmacology)
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