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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms of Reproduction and Reproductive Diseases
edited by
submission deadline 22 Sep 2025 | Viewed by 58 | Submission Open
Keywords: reproduction; implantation; fertilization; gametogenesis; preimplantation genetic testing; in vitro fertilization; infertility; miscarriage; reproductive aging; endometriosis; premature ovarian failure; menopause; preeclampsia; preterm birth; placenta; testis; azoospermia
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Natural Products in Lifestyle-Related Diseases: Molecular Mechanisms, Prevention and Treatments
edited by
submission deadline 25 Sep 2025 | 2 articles | Viewed by 3571 | Submission Open
Keywords: natural products; crude drugs; lifestyle-related diseases; diabetes mellitus; cardiovascular disease; non-alcoholic hepatosteatosis; cancer; sarcopenia; Alzheimer’ s disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Periodontal Disease, Association with Systemic Conditions and Periodontal Pathogens: 2nd Edition
edited by Evangelos Papathanasiou
submission deadline 25 Sep 2025 | 1 articles | Viewed by 1678 | Submission Open
Keywords: periodontal disease; periodontitis; periodontal medicine; periodontal– systemic interactions; immune response; periodontal pathogens
(This special issue belongs to the Section Molecular Immunology)
Antitumor Activity of Natural Products submission deadline 25 Sep 2025 | 1 articles | Viewed by 962 | Submission Open
Keywords: natural compounds and extracts with antitumor activity; studies on molecular mechanisms; signal transduction modulation in tumor cells; immunomodulating activity; mitosis inhibition; cell differentiation; cell death induction (apoptosis/autophagy)
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Unveiling Molecular Mysteries of Brain Barriers
edited by Ana Catarina Duarte
submission deadline 25 Sep 2025 | Viewed by 120 | Submission Open
Keywords: blood– brain barrier; blood– cerebrospinal fluid barrier; arachnoid barrier; transport mechanisms; drug delivery; drug metabolism; ATP-binding cassete (ABC) transporters
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Epigenetic Mechanisms in Cognition
edited by Sabrina Venditti
submission deadline 25 Sep 2025 | Viewed by 103 | Submission Open
Keywords: epigenetics; DNA methylation; histone modifications; noncoding RNAs; cognition; learning and memory; neuroplasticity; neurodegeneration; ASD; training
(This special issue belongs to the Section Molecular Biology)
Molecular Insights into Magnetic Materials: Synthesis, and Applications
edited by Artur Chrobak
submission deadline 25 Sep 2025 | Viewed by 93 | Submission Open
Keywords: magnetic materials; properties; synthesis; applications
(This special issue belongs to the Section Materials Science)
Accelerating Therapeutic Innovation: Advances in Computer-Aided Drug Discovery
edited by Pietro Delre and
submission deadline 25 Sep 2025 | Viewed by 86 | Submission Open
Keywords: CADD; drug discovery; machine learning; virtual screening; drug-target interaction
(This special issue belongs to the Section Molecular Informatics)
Molecular Insights in Neurodegeneration submission deadline 25 Sep 2025 | Viewed by 80 | Submission Open
Keywords: neurodegeneration; molecular mechanisms; protein aggregation; neuroinflammation; oxidative stress; mitochondrial dysfunction; Alzheimer’ s disease; Parkinson’ s disease; biomarkers; therapeutic targets
(This special issue belongs to the Section Molecular Neurobiology)
Biomarker Discovery in Oral Diseases: Integrating Connected Health and Digital Biomarkers for Advanced Diagnostics and Personalized Care submission deadline 25 Sep 2025 | Viewed by 57 | Submission Open
Keywords: oral diseases; biomarker; proteomics; metabolomics
(This special issue belongs to the Section Molecular Biology)
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