Advances in the Translational Preclinical Research
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 May 2026 | Viewed by 1774
Special Issue Editor
Special Issue Information
Dear Colleagues,
Despite significant advances in cancer research, substantial challenges persist in the fight against this disease. Translational preclinical research plays a crucial role in this process by generating essential data to enhance drug efficacy, minimize toxicity, and establish effective management protocols. In the early stages of developing a novel therapy, the drug discovery process focuses on identifying and developing compounds that specifically target validated cancer pathways. Once a lead compound is selected, it undergoes an optimization process to improve its potency, selectivity, and safety profile. Throughout this process, in silico, in vitro, and in vivo experiments are conducted to deepen the understanding of the biological mechanisms underlying the evaluated cancer treatment. This Special Issue seeks to showcase original preclinical research focused on the evaluation of innovative drugs and treatments, also highlighting ongoing efforts to translate scientific discoveries into effective cancer therapies with the potential to benefit patients.
Dr. Mariano Gabri
Guest Editor
Manuscript Submission Information
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Keywords
- translational preclinical research
- drug discovery
- cancer therapies
- in vitro and in vivo experiments
- biological mechanisms
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