Water-Soluble Complexes: Catalytic and Biologic Applications 2.0

Dear Colleagues,

Rapid developments in the field of catalysis are leading to an increased demand for tailor-made catalysts. Water-soluble transition-metal complexes are attracting a continuously growing interest for catalytic applications, owing to their environmentally friendly processing, simple product separation, and pH-dependent selectivity in aqueous media. Moreover, the search for industrial processes with reduced environmental impact has prompted research on nonconventional solvents. Among the alternatives, water is the green solvent par excellence, as it is nontoxic, safe (even for large-scale applications), readily available, environmentally benign, and inexpensive.

On the other hand, the bioavailability and bioactivity of coordination compounds are often dependent on their hydrosolubility. Therefore, in the search for new bioactive agents as well as in the design of new potentially active metallodrugs, it is of paramount importance, beyond the nature of the metal, to choose appropriate ligands, which affect the thermodynamic and kinetic stability, the solubility, and the lipophilicity of the complexes.

The current Special Issue of IJMS represents an excellent platform for the discussion of recent developments in this field at the molecular level. It welcomes studies on fundamental aspects and applications that can synergically merge in the platform to provide a comprehensive coverage of the field and the bases to boost a rational development of new systems.

Dr. Luísa Margarida Martins
Guest Editor

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