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Special Issue "Transposable Elements"
Deadline for manuscript submissions: 31 January 2020.
Prof. Dr. Teresa Capriglione Website E-Mail
Dipartimento di Biologia, Università di Napoli "Federico II", Complesso Universitario di Monte S. Angelo, Via Cinthia, 80126, Napoli, Italia
Interests: PCR; DNA; cloning; molecular biology; RNA; DNA sequencing; molecular genetics; genomics sequencing; molecular cloning; bioinformatics; phylogenetic analysis; chromosomes; gene expression and chromatin biology; microsatellites; cytogenetics; in situ hybridization; developmental neuroscience; hybridization; developmental genetics; vertebrates; southern blot; Y chromosome; centromere; polyploidy; transposable elements; transposons; MirBase
Dr. Andrea Luchetti Website E-Mail
Dipartimento di Scienze Biologiche, Geologiche e Ambientali, Università di Bologna, via Selmi 3, 40126, Bologna, Italy
Interests: DNA; DNA sequencing; genomics; genetics; phylogenetic analysis; population genetics; genetic diversity; phylogenetics; molecular ecology; phylogeny; insect; molecular phylogenetics; phylogeography and phylogenetic biogeography; microsatellites; evolutionary genetics; DNA barcoding; hybridization; molecular taxonomy; nucleic acids; transposable elements; retrotransposons; gynogenesis
Transposable elements are discrete DNA sequences ubiquitous among prokaryotic and eukaryotic genomes. The ability to self-replicate and move within and among chromosomes, inserting in both coding and non-coding regions, makes transposable elements particularly important for genome functionality and evolution. After their first discovery nearly 70 years ago, transposable elements were considered mostly deleterious for host genomes: a kind of genomic parasite. Despite their selfish nature, later studies indicated their high natural abundance within genomes (up to 50% in some instances) and their implications for genome evolution.
Nowadays, the implication of transposable elements in many biological processes is well known, including speciation, adaptation, horizontal transfer, and pathological conditions in humans. At the genome level, transposable elements are currently recognized as a powerful source of genetic variation, genomic restructuring, and gene expression modulation . Moreover, a growing body of evidence highlights events of exaptation, in which transposable element sequences have been “recruited” by host genomes and integrated in gene structures and/or gene regulatory networks. Transposable elements have even been found to play a role in development, neurogenesis, and ageing.
In recent years, the use of transposable elements as a means of genomic modification and transgenesis has been envisaged and, effectively, put into practice. Today, some engineered transposable elements are used for gene transfer therapy.
In the current “genomic era”, in which NGS technologies allow the sequencing and assembly of many genomes and transcriptomes, studies of transposable elements have been boosted by the huge quantity of sequence information available. Therefore, we are now in an exciting moment for transposable element studies! The present Special Issue aims to gather current knowledge from past studies, and from cutting-edge transposable element research, by selecting papers on hot topics of transposable element biology. Therefore, studies based on experimental evidence, suggesting or updating evolutionary models, and dealing with applications are well suited for this Special Issue.
Prof. Dr. Teresa Capriglione
Dr. Andrea Luchetti
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- jumping gene
- DNA transposon
- endogenous retrovirus
- reverse transcription
- genome evolution
- genomic modification
- gene structure