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Special Issue "Metal Metabolism in Animals II"
Deadline for manuscript submissions: closed (18 June 2017).
Prof. Dr. Reinhard Dallinger Website E-Mail
Institute of Zoology, University of Innsbruck, Technikerstr. 25, 6020 Innsbruck, Austria
Interests: environmental toxicology and ecotoxicology; molecular physiology; microevolution of metal sensitivity; evolution, biochemistry and gene regulation of metallothioneins; metal-specific pathways in animal physiology; metal detoxification; metal-related biological indicators and biomarkers
The publication in this journal of the Special Issue on “Metal Metabolism in Animals” in 2015 was a great success, which can be accessed at https://www.mdpi.com/journal/ijms/special_issues/metal-metab-animal. It was instantly clear that this topic was quite diverse and complex. This is not only due to the physico-chemical variety of metals, many of them following distinct metabolic pathways or inducing specific pathological interactions within animal cells; in fact, many essential metallic trace elements serve—even at very low concentrations—as indispensable triggers of cellular regulatory processes, as they are constituents of enzymes, vitamins, and other bio-molecules. On the other hand, both essential and non-essential trace elements can exert toxic effects, if their intracellular concentrations exceed the limits of their specific tolerable range. Yet, we cannot be sure of the exact number of essential trace metals, so in the future it is possible that additional trace elements will have to be added to this number.
In the first issue of “Metal Metabolism in Animals”, topics such as metal tolerance and detoxification in non-model organisms, metal allergy, immunology and cytotoxicity, trace element homeostasis and interaction with metallo-enzymes, and the theoretical background of the biological role of metals in living systems were addressed. All these different subjects were discussed by a unified approach which was defined and circumscribed in a general manner as “metallomics” (see Dallinger 2015, introduction to the first issue of “Metal Metabolism in Animals” at https://www.mdpi.com/journal/ijms/special_issues/metal-metab-animal).
However, the editors feel that the first issue of “Metal Metabolism in Animals”, while having addressed a range of important topics, is far from exhaustive, and many subjects in this field were not touched upon. For example, the human dimension of trace element metabolism was not discussed, nor have the more ecologically oriented aspects of metal uptake and metabolism by animals exposed to metal-contaminated environments been sufficiently addressed. It was therefore decided to produce a second Special Issue of “Metal Metabolism in Animals”, in order to include so far neglected or less considered subjects in this field.
In particular, we welcome (in addition to the topics mentioned in the introduction of the first issue) topics such as the following:
- Trace element uptake, regulation, and homeostasis in human nutrition;
- All aspects of trace element deficiency in animals and humans;
- Metal interaction with metallo-enzymes and their role in human and animal metabolism;
- Metal interactions with vitamins and metabolic implications;
- Metal ion availability in contaminated environments and its implication for metal accumulation and toxicological interactions in exposed animals;
- Evolutionary, microevolutionary, and population-specific effects of metals on animal species in both the laboratory and in the wild;
- Any other topic that focuses, in an integrative manner, on metal metabolism in animals, by addressing molecular and physiological aspects.
Prof. Dr. Reinhard Dallinger
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Metal homeostasis
- Metal toxicology
- Metal deficiency
- Metallo-enzymes and Metallo-proteins
- Metal contamination and exposure