Special Issue "Glycosylation and Glycoproteins 2017"
Deadline for manuscript submissions: closed (31 December 2017) | Viewed by 28602
Interests: protein glycosylation; regulation of glycosylation reactions; roles of glycosylation in development and disease
Special Issues, Collections and Topics in MDPI journals
This Special Issue is the continuation of our 2015 Special Issue, "Glycosylation and Glycoproteins" (https://www.mdpi.com/journal/ijms/special_issues/glyco).
Sugars, which represent one of the four fundamental building blocks of life, are the most abundant biological molecules on our planet. Sugars can be combined in a myriad number of ways to form complex carbohydrate structures (glycans). The glycan repertoire (glycome) of a given cell or organism is thus many orders of magnitude more complex than the genome or the proteome. However, only over the past two decades have we begun to truly appreciate the extent to which glycan function permeates biological systems, including human health and disease.
Glycosylation is the process by which a sugar is enzymatically attached to proteins, lipids, or other organic molecules. In particular, glycosylation increases protein diversity and structure, and as such significantly impacts on the function of the resulting glycoprotein.
As the roles of glycosylation in physiological and pathological processes are increasingly being recognized, the field of glycobiology is eliciting an unprecedented interest. However, the extreme complexity and structural diversity of glycans, combined with their “non-template”-driven synthesis, pose a significant technical challenge that has stimulated advances in the field.
This Special Issue will welcome contributions in all areas of glycobiology, including studies on the function of glycans in basic biological processes and human diseases, and the regulation of glycosylation reactions in vivo, as well as technical advances to analyze the complexities of the glycoproteome.
Prof. Dr. Patricia Berninsone
Assoc. Prof. Dr. Joe Tiralongo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- glycosyl donor
- glycosyl acceptor
- glycosidic bond
- oligosaccharide chain
- glycoprotein IIb/IIIa
- zona pellucida
- histocompatibility antigens
- human chorionic gonadotropin (HCG)
- thyroid-stimulating hormone (TSH)