Regulation of Erythropoiesis 3.0

Dear Colleagues,

Approximately 84% of the cells in the human body are red blood cells. Erythropoiesis is the complex process that produces mature red blood cells (erythrocytes) from erythropoietic stem cells, and mature red blood cells in mammals uniquely lack a cell nucleus and most organelle, with some exceptions in some salamanders and fish. Genetic diseases, such as sickle cell anemia and hereditary persistence of fetal hemoglobin (HPFH) and erythroleukemia, have been studied as a model for gene expression control and for molecular genetic understanding and treatment development. However, although considerable advances in the understanding of erythropoiesis and hemoglobin switching have occurred, the fundamental molecular mechanism of the regulation of erythropoiesis and globin switching is still not understood

This Special Issue on the regulation of erythropoiesis will include a selection of original papers and reviews focused on genetic and cellular bases and molecular mechanisms of erythroid differentiation and globin switching, including epigenetic connections between the gene regulatory network and chromatin dynamics, cell signaling, recent progress in single cell genomics, and various new pathophysiologic mechanisms.

Prof. Dr. Chul Geun Kim
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.