Cancer Immunology with a Focus on Understudied Cancers as Targets for Immunotherapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 June 2016) | Viewed by 87235
Special Issue Editor
2. Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, Charleston, SC 29425, USA
Interests: head and neck squamous cell carcinoma; HNSCC; immune regulation; immunotherapy; premalignant oral lesions
Special Issue Information
Dear Colleagues,
While decades have passed since the declaration of the war on cancer, progress in the battle has not been uniform for all cancer types. For certain, many advances have been made and there exists a spectrum of surgical, chemotherapeutic and radiological treatment approaches. In recent years, immunotherapeutic approaches have become increasingly more prominent, with melanoma being most prominently targeted in immunological treatment trials. Challenges in optimal use of immunotherapy include tumor-induced immune subversion, its compatibility with other conventional treatments, extent of tumor immunogenicity, immune-prevention strategies, and understanding the limitations of immunotherapy. This issue aims to discuss these challenges in particular as they relate to cancers that have been understudied as candidates for immunotherapy. It is with a wider scope of understanding of the immunological challenges posed by the heterogeneity of cancers that customized immunotherapy can be included in the armament for cancers that have not been in the forefront of immunological treatment investigations.
Prof. Dr. M. Rita I. Young
Guest Editor
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Keywords
- immunotherapy
- cancer vaccines
- immune subversion
- cancer
- immunosuppression
- cytokines
- immune regulation
- cancer prevention
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