(Meta)Genomic, Functional, Structural and Evolutionary Analysis of Transport Systems
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 31 October 2024 | Viewed by 7093
Special Issue Editors
Interests: bioinformatics; transport biology; molecular evolution; genomics
Interests: molecular biology; transport biology; bioinformatics; genomics
Special Issue Information
Dear Colleagues,
Molecular transport systems are essential for life. They move molecules in and out of cells as well as organelles, thus playing critical roles in organismal physiology, homeostasis, and cell–cell communication. Transport proteins include channels, secondary carriers, primary active transporters, group translocators, and transmembrane electron carriers that selectively allow the passage of substrates through membranes. Whether transport is active or passive (depending on the energy requirements of the process), when transporters malfunction there can be catastrophic consequences for a cell. Due to their relevance to human health, more than 50% of all FDA-approved drugs target integral membrane proteins. This Special Issue presents a collection of papers conveying the state of the art in transport biology. These papers describe research ranging from experimental to bioinformatic approaches, contributing toward expanding our functional, evolutionary, and mechanistic understanding of transport systems in all domains of life.
The scope of this Special Issue will cover (but is not limited to) the following areas:
- Gene mutation and regulatory mechanisms of transport systems.
- Bioinformatics approaches to the study of transport systems.
- Ecological impact of molecular transport systems.
- Genomic and metagenomic analyses of transport systems.
- Three-dimensional structural approaches to the study of transport systems.
- Evolutionary analyses of transport systems.
Dr. Arturo Medrano-Soto
Dr. Milton Saier
Dr. Gabriel Moreno-Hagelsieb
Guest Editors
Manuscript Submission Information
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Keywords
- molecular transport
- transport mechanisms
- evolution
- families and superfamilies
- genomics
- metagenomics
- 3D structural insights
- bioinformatics
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