Molecular Advances in the Pathophysiology and Therapy of Cerebral Gliomas
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 11
Special Issue Editor
2. Department of Human Neurosciences, Division of Neurosurgery, Policlinico Umberto I University Hospital, Sapienza, University of Rome, 00157 Rome, Italy
Interests: glioblastoma ultrastructural; morphological biomarkers; diffuse low-grade gliomas
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Molecular markers are crucial for classifying and treating cerebral gliomas, and scientific investigations can provide novel therapeutic and diagnostic opportunities. This Special Issue aims to highlight research efforts made in the identification and characterization of new molecular markers, facilitating the development of more effective diagnostic and therapeutic strategies to combat gliomas.
We welcome the submission of original research articles, reviews and meta-analysis articles, seeking to disseminate the most recent findings regarding the molecular basis of neuro-oncology. We are particularly interested in articles that offer novel perspectives on pathophysiological mechanisms that could be employed to develop innovative diagnostic and therapeutic strategies. Potential topics include, but are not limited to, the following:
- Molecular markers of cerebral gliomas and brain tumor pathogenesis;
- Target therapy for gliomas;
- Gene therapy;
- Viral and non-viral vectors;
- HSV1-TK,
- Mutant IDH1 3,
- Immunotherapy,
- FMS-like tyrosine kinase 3 ligands;
- The pathophysiology of cerebral gliomas;
- Molecular prognostic factors in cerebral gliomas;
- Autophagy related to the biology of gliomas;
- The role of micro-RNA in the pathogenesis of glial brain tumors;
- Cytoskeletal proteins of gliomas;
- Ultrastructural molecular markers of brain tumors;
- Molecular targeted therapy for gliomas.
This Special Issue will be supervised by Dr. Placido Bruzzaniti , with assistance from PhD MD Student Giovanni Pennisi (Fondazione Policlinico Universitario Agostino Gemelli IRCCS) and PhD MD Biagia La Pira (ASST Santi Paolo e Carlo).
Dr. Placido Bruzzaniti
Guest Editor
Manuscript Submission Information
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Keywords
- mutant IDH1 3
- EVs
- Ki67
- HSV1-TK
- glioma
- lipid vesicles
- viral vectors
- ATRX
- EGFR
- IDH1
- MGMT
- 1p/19q codeletion
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