Neurodevelopmental Disorders: From Molecular and Cellular Mechanisms to Therapeutic Perspectives

Dear Colleagues,

Neuronal progenitor cells proliferate and divide in the developing brain and then exit the cell cycle. Post-mitotic neurons migrate to their final destination, followed by neuronal morphogenesis, such as neurite formation, spine formation, and synaptogenesis. They play a significant role in the formation and establishment of neural connectivity, which affects neural activity and behavior. These complex cellular events can be attributed to a variety of molecules. If any of these cellular events fail, it results in neurodevelopmental disorders, such as autism spectrum disorder (ASD) or attention deficit hyperactivity disorder (ADHD). Therefore, the elucidation of the underlying cellular and molecular mechanisms and identification of the molecules responsible are urgently required.

This Special Issue seeks original articles and review articles about molecules implicated in neurodevelopmental disorders. In addition to articles that address neurodevelopmental disorders, we are also interested in articles that address associated disorders, such as seizure and anxiety disorder. Additionally, we are interested in articles that describe how regulatory molecules function in cellular and molecular processes in normal brain development and behavior, which can provide insight into the causes of neurodevelopmental disorders.

Dr. Kazuhito Toyooka
Guest Editor

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