The Effect of Natural Products on Obesity, Aging, and Longevity

Dear Colleagues,

It is a widely held theory that our genes define who we are when we are born. Genetic polymorphisms can allow for the prediction of our physical appearance, our metabolism, and even our longevity. Nevertheless, they do not change—the prediction of risks sees itself maintained whether at birth or at an advanced age. As such, many genetic mutations have no effect on the organism due to the complex nature of gene–environment interactions, which then results in reduced penetrance. By contrast, epigenetic modifications in the form of DNA methylation patterns, for example, reflect a current status of health or disease, are sensitive to environmental effects, and are actionable—able to change upon intervention. Natural products are known to be powerful modifiers of the epigenome—thus, by extension, modifiers of human metabolism and longevity as well. Therefore, in this Special Issue, we aim to explore the effect of natural products on various aspects of human metabolism, healthy aging, and longevity.

This Special Issue is supervised by Prof. Dr. Igor Kovalchuk and assisted by our Topical Advisory Panel Member Dr. Esmaeel Ghasemi-Gojan (University of Lethbridge).

Prof. Dr. Igor Kovalchuk
Guest Editor

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• natural products
• metabolism
• aging
• longevity