Molecular Mechanisms of an Aberrant Specific Immune Response: Role in Pathogenesis of Infectious, Autoimmune Diseases and Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (20 February 2023) | Viewed by 41947
Special Issue Editors
Interests: immune response; cytotoxic T cells; B cells; antibodies; autoantibodies; cytokines; antibody dependent cytotoxicity; pathogen associated molecular patterns; pathogen recognition receptors
Special Issues, Collections and Topics in MDPI journals
Interests: immune response; infections; autoimmune response
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The aim of a specific immune response is protection against infection and cancer while supporting repair and limiting tissue damage. A specific immune response is initiated upon exposure to a pathogen recognition pattern, damage-associated molecular pattern molecules, and tumor-associated antigens. These ligands are sensed by the pattern recognition receptors, initiating a specific immune response. This immune response involves the successful clearance of pathogens or abnormal host cells and establishes immune memory. However, in some circumstances, this specific immune response can target host tissues, damaging normal structures. This abberant immune response can maintain and extend destruction, imparing the function of tissues and organs. Impaired organ function can impact a patient’s longevity and the quality of a patient’s life. We invite authors to submit original research papers and review articles related to the following potential list of topics:
- Aberrant molecular mechanisms of T and B lymphocyte development, activation, and function in infection, autoimmunity, and cancer;
- The role of bioactive molecules (cytokines, chemokines, interferons, growth factors) in aberrant immune responses;
- Role of antibody-dependent cytotoxicity in tissue damage and the failure of immune protection;
- Genetic markers of aberrant immune responses;
- Role of antibodies and autoantibodies in aberrant immune responses;
- Role of PAMPS, DAMPS, and PRR in immune responses to infection, autoimmunity, and cancer.
Dr. Svetlana Khaiboullina
Dr. Ekaterina Martynova
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- immune response
- cytotoxic T cells
- B cells
- antibodies
- autoantibodies
- cytokines
- antibody dependent cytotoxicity
- virus
- microbe
- pathogen-associated molecular patterns
- pathogen recognition receptors
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.