Molecular Findings in Colorectal Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 November 2024) | Viewed by 974
Special Issue Editor
Interests: p53; cancers; tumor suppression; chemotherapy; transcriptomics; genomics; p53 gene family; transcriptional regulation; next-generation sequencing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Colorectal cancer is one of the most widespread cancers in the world. Despite the many studies conducted in the field to date, a high rate of mortality and the development of anticancer treatments represent challenging battles.To date, a lot of information has been collected about the molecular mechanisms at the basis of the onset and progression of colorectal cancer, and many genes/proteins as well as regulating molecules have been linked to this tumor. Above all, in recent years NGS technologies have represented a key way by which immeasurable data have become obtainable, helping to better understand the cancer from a transcriptomic, genomic, metabolomic as well as metagenomic point of view, through a multi-omics approach.These data permit researchers to shed light and develop new diagnostic tools as well as therapeutical strategies against colorectal cancer.
This Special Issue aims to collect all the latest research and discoveries in this field in order to elucidate the molecular mechanisms underlying the development of colorectal cancer, exploring pharmaceutical and therapeutical applications to counteract it. The original research or review papers are all welcome.
Dr. Mariano Francesco Caratozzolo
Guest Editor
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Keywords
- colorectal cancer
- molecular mechanisms
- NGS technologies
- multi-omics
- molecular diagnosis and treatment
- pharmacology
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