New Insights in Biomarkers of Autoimmune and Autoinflammatory Diseases: 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 30 August 2025 | Viewed by 64
Special Issue Editor
2. Fondazione Policlinico Universitario “A. Gemelli” IRCCS, 00168 Rome, Italy
Interests: immunology; autoimmunity; inflammation; biomarkers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The deregulation of innate and adaptive immune systems affects 5% of the worldwide population, with a high impact in terms of clinical impairment, morbidity, and, due to chronic conditions, a significant economic burden in the long run. Inflammation, the crux of innate immunity, is a mediator of effects that may be involved or in itself deregulated in the absence of an auto-immune attack, allowing for the precipitation of conditions included under the umbrella of autoinflammatory diseases. Accordingly, cellular and molecular biomarkers are largely involved in the diagnosis, prognosis, response to therapies, and follow-up, providing a prediction of changes in disease activity. Taking into account individual and genetic susceptibility as well as the wide range of environment risk factors involved in pathogenesis, research to set-up and validate novel, effective, and personalised biomarkers of autoimmune and autoinflammatory conditions is vital. This Special Issue is devoted to showcasing the most recent results aimed at exploiting the clinical potential of biomarkers that measure disordered immune response.
Potential topics include, but are not limited to, the following:
- Innate immunity;
- Adaptive immunity;
- Inflammation;
- Immunoglobulins;
- Autoantibodies;
- Free light chains;
- Peptides;
- Cytokines;
- Receptors;
- Leukocytes;
- Extracellular vesicles;
- Signal transduction;
- Inflammaging;
- Inflammasome.
Dr. Mariapaola Marino
Guest Editor
Manuscript Submission Information
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Keywords
- inflammaging
- inflammasome
- autoantibodies
- free light chains
- cytokines
- receptor
- signal transduction
- innate immunity
- adaptive immunity
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