Current Research for Castration Resistance Prostate Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (20 January 2025) | Viewed by 5097
Special Issue Editor
Special Issue Information
Dear Colleagues,
Prostate cancer (CaP) is the second most common cancer in terms of incidence and the fifth most common cancer death in men worldwide. Treatment approaches and prognosis for CaP depend on its stage at diagnosis. Initially, CaP is treated with androgen deprivation therapy with a good initial response but followed by inevitable relapse. In recent years, new therapies based on inhibition of the androgen receptor pathway or taxanes have been developed, in particular to combat the phenomenon of castration resistance. However, the emergence of resistance clearly limits their benefits and their use. Not all mechanisms leading to castration resistance and treatment resistance in CaP have been elucidated. Similarly, these resistances demonstrate the potential need for the development of new therapies.
The Special Issue focuses on new advances in the mechanisms of castration resistance and therapeutic resistance in prostate cancer and in new treatments for CRPC.
Dr. Virginie Firlej
Guest Editor
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Keywords
- prostate cancer
- castration-resistant prostate cancer
- therapy resistance
- biomarkers
- androgen receptor
- new therapies
- tumor microenvironment
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