Molecular Biology of Extremophiles: Recent Advances
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 October 2025 | Viewed by 650
Special Issue Editor
Special Issue Information
Dear Colleagues,
Extremophiles are microorganisms that thrive in conditions previously thought to be incompatible with life, for example, living under extreme temperatures, pH values, salinity, radiation, or pressure. For these organisms, this hostility represents an ideal environment, challenging our understanding of life's limits. Advances in genomics, transcriptomics, proteomics, and metabolomics have revolutionized our ability to study extremophiles at the molecular level, shedding light on their adaptive strategies, evolutionary pathways, and potential applications in medicine, industry, and astrobiology.
Scope of the Special Issue:
This Special Issue will showcase cutting-edge research on microbial extremophiles (bacteria, Archaea, fungi, and microalgae) across multiple disciplines, fostering a comprehensive understanding of all aspects of extremophiles, including potential applications in science and industry.
We welcome original research articles, reviews, and perspectives contributions addressing the following topics:
- Functional genomics, transcriptomics, proteomics, and metabolomics of extremophiles;
- Bioprospecting and biotechnological applications of novel biomolecules;
- Evolutionary and phylogenetic insights into extremophilic microorganisms;
- Molecular mechanisms behind adaptation to extreme environments;
- Microbial interactions and extremophile ecology;
- Synthetic biology and metabolic engineering of extremophiles.
We particularly encourage the submission of studies that integrate multi-omics approaches, biochemical analyses, and genetic engineering to uncover novel aspects of microbial life in extreme habitats and their untapped potential.
We look forward to receiving your contributions.
Please join us in expanding our understanding of microbial extremophiles.
Dr. Paulina Corral
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- extremophiles
- multi-omics approaches
- secondary metabolites
- bioactive compounds
- genome mining
- phylogeny and evolution
- bioprospecting
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