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State-of-the-Art Molecular Microbiology in Italy

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 2405

Special Issue Editor


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Collection Editor
Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Interests: industrial yeasts biotechnology

Special Issue Information

Dear Colleagues,

This Topical Collection aims to provide a comprehensive overview of recent advances in molecular microbiology in Italy by inviting contributions from Italian research institutes/laboratories that consolidate our understanding of this area. Topics include, but are not limited to, the following:

  • Antibiotic resistance mechanisms;
  • Biosynthesis of macromolecules;
  • Cell division and cell wall structure;
  • Gene expression and its regulation;
  • Gene transfer mechanisms;
  • Host–pathogen interactions including host responses;
  • Induction of cell death by microorganisms;
  • Membrane biogenesis and function;
  • Pathogenicity mechanisms;
  • Posttranslational modifications;
  • Protein delivery (secretion and trafficking);
  • Signaling pathways and networks;
  • Systems biology;
  • Vaccines;
  • Virulence factors;
  • Antimicrobial peptides;
  • Therapeutic strategies.

Prof. Dr. Danilo Porro
Collection Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecular microbiology
  • gene expression regulation
  • biochemical processes
  • pathogenicity mechanisms
  • host-microbe interactions
  • bacteriophages
  • therapeutic strategies

Published Papers (1 paper)

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Research

10 pages, 3913 KiB  
Article
Crossing Bacterial Genomic Features and Methylation Patterns with MeStudio: An Epigenomic Analysis Tool
by Christopher Riccardi, Iacopo Passeri, Lisa Cangioli, Camilla Fagorzi, Marco Fondi and Alessio Mengoni
Int. J. Mol. Sci. 2023, 24(1), 159; https://doi.org/10.3390/ijms24010159 - 21 Dec 2022
Cited by 1 | Viewed by 1883
Abstract
DNA methylation is one of the most observed epigenetic modifications. It is present in eukaryotes and prokaryotes and is related to several biological phenomena, including gene flow and adaptation to environmental conditions. The widespread use of third-generation sequencing technologies allows direct and easy [...] Read more.
DNA methylation is one of the most observed epigenetic modifications. It is present in eukaryotes and prokaryotes and is related to several biological phenomena, including gene flow and adaptation to environmental conditions. The widespread use of third-generation sequencing technologies allows direct and easy detection of genome-wide methylation profiles, offering increasing opportunities to understand and exploit the epigenomic landscape of individuals and populations. Here, we present a pipeline named MeStudio, with the aim of analyzing and combining genome-wide methylation profiles with genomic features. Outputs report the presence of DNA methylation in coding sequences (CDSs) and noncoding sequences, including both intergenic sequences and sequences upstream of the CDS. We apply this novel tool, showing the usage and performance of MeStudio, on a set of single-molecule real-time sequencing outputs from strains of the bacterial species Sinorhizobium meliloti. Full article
(This article belongs to the Special Issue State-of-the-Art Molecular Microbiology in Italy)
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