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Cardiology and Vascular Health: From Molecular Mechanisms to Therapies

This special issue belongs to the section “Molecular Genetics and Genomics“.

Special Issue Information

Dear Colleagues,

Attaining cardiovascular health involves understanding the cellular, molecular, ionic pathways and their genetics involved in the induction and treatment of cardiovascular diseases. The enormous numbers of factors involved in the process leading to cardiovascular disease sometimes exceed the capacity of the mind to integrate them in a meaning way. The use of computer algorithms (machine learning) holds the promise identifying patterns that may not be readily apparent. Conditions such as atherosclerosis, heart failure, cardiomyopathy, coronary artery disease, cardiac arrhythmias, valvular heart disease, as well as diseases of the aorta and small vessels remain challenges for cardiovascular medicine.  Pharmacologic therapy is based on understanding the fundamental basis of the disease whether it is a cardiac ion channel disorder, a receptor defect or another kind of disorder.

The aims of this Special issue of IJMS are several fold. It aims to create an understanding of the best machine learning approaches to unravel basic molecular, cellular genetic and other mechanism and pathways leading to the different kinds of cardiovascular disease. It also aims to synthesize the approaches whereby machine learning technology can lead to interventions or drug discovery that can treat or prevent cardiovascular diseases leading to improved cardiovascular health.

Pure clinical studies are out of scope of this Special Issue, however, clinical submissions with biomolecular experiments are welcome.

Prof. Dr. Simon W. Rabkin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Machine learning
  • cardiovascular molecular biology
  • signal transduction
  • genetics
  • ion channels
  • drug discovery
  • arrhythmias
  • heart failure
  • aortic diseases
  • Valvular heart disease
  • Atherosclerosis

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Int. J. Mol. Sci. - ISSN 1422-0067