Recent Advances in Chromatin Structure and Dynamics
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 1501
Special Issue Editor
Special Issue Information
Dear Colleagues,
The complexity of chromatin folding in the eukaryotic nucleus has captivated researchers worldwide for over fifty years. From the early days of electron microscopy images to revolutionary chromosome conformation caption techniques for measuring genomic interactions, and now to advanced methodologies such as super-resolution microscopy, next-generation sequencing, single-cell techniques, and high-resolution genome modeling, the study of chromatin architecture has yielded invaluable insights into the role of genome multiscale organization in various cellular processes and human diseases.
We now understand that the genome is hierarchically organized into loops, topologically associated domains, compartments, and chromosome territories. Additionally, epigenetic regulation through post-translational modifications of histone tails, DNA methylation, histone variants, and protein binding provides a diverse array of mechanisms for modulating chromatin structure and dynamics, which in turn influences gene expression.
In this Special Issue, we invite researchers to submit original articles and reviews that focus on chromatin structure and dynamics, as well as its regulation by epigenetic modifications in the context of cellular function and human diseases.
Dr. Stephanie Portillo-Ledesma
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- chromatin structure and dynamics
- genome architecture
- epigenetic regulation
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