Latest Research in Natural Bioactive Compounds
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 77
Special Issue Editor
Special Issue Information
Dear Colleagues,
Natural bioactive compounds continue to attract increasing scientific interest due to their broad spectrum of biological activities and favorable safety profiles. Polyphenols, flavonoids, terpenes, alkaloids, and other plant-derived constituents demonstrate antioxidant, anti-inflammatory, antimicrobial, anticancer, and regenerative properties. Despite promising pharmacological potential, many natural compounds face significant challenges, including low solubility, limited stability, poor permeability, and insufficient bioavailability. Modern pharmaceutical technology, biomaterials science, and nanotechnology now provide advanced strategies to overcome these limitations. The integration of innovative drug delivery systems, such as nanoparticles, nanofibers, hydrogels, 3D-printed scaffolds, and mucoadhesive platforms, creates new opportunities for improving the therapeutic performance of natural compounds.
We are pleased to invite you to contribute to this Special Issue, which aims to highlight cutting-edge research and emerging trends in this rapidly developing field. This Special Issue aims to collect high-quality research and review articles that explore new advances in natural bioactive compounds, from fundamental phytochemical investigations to formulation development and clinical relevance. The topic aligns with the journal’s scope by combining pharmaceutical sciences, biomaterials, drug delivery, and translational biomedical research. Attention will be given to interdisciplinary approaches bridging natural product research with modern formulation technologies and evidence-based therapeutic evaluation.
Authors are invited to submit original research articles and reviews to this Special Issue. Research areas may include, but are not limited to, the following:
- Isolation and phytochemical characterization of natural compounds;
- Biological activity studies;
- Strategies to enhance solubility, stability, and bioavailability;
- Nanotechnology-based delivery systems for natural compounds;
- Mucoadhesive and targeted delivery approaches;
- Biopolymer-based systems;
- Translational and clinical perspectives on natural bioactives
Dr. Magdalena Paczkowska
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bioactive compounds
- natural products
- polyphenols
- flavonoids
- terpenes
- alkaloids
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