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Enhanced Anticancer Properties of Natural Products

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 20 July 2025 | Viewed by 275

Special Issue Editors


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Guest Editor
Department of Internal Medicine, Institute of Medical Science, Gyeongsang National University Hospital, College of Medicine, Gyeongsang National University, 15 Jinju-daero 816 Beon-gil, Jinju 52727, Republic of Korea
Interests: cancer cell biology; natual products; anticancer properties; cell death mechanism; cell morphology; proteomics; bioinformatics; signal transduction; drug resistance; chemotherapy
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Guest Editor
Department of Internal Medicine, Institute of Medical Science, Gyeongsang National University Hospital, College of Medicine, Gyeongsang National University, 15 Jinju-daero 816 Beon-gil, Jinju 52727, Republic of Korea
Interests: cancer cell biology; natual products; anticancer properties; cell death mechanism; cell morphology; proteomics; bioinformatics; signal transduction; drug resistance; chemotherapy

Special Issue Information

Dear Colleagues,

Natural products derived from plants demonstrate various biological activities, including antioxidant, anti-inflammatory, and anticancer properties, depending on their chemical structure and cellular circumstance. Recent studies suggest that the combination treatment of anticancer drugs with lower toxicity may be a more effective chemotherapeutic strategy than single treatment of a high dosage. The aim of this Special Issue is to reveal the enhanced anticancer properties of natural products using a new combination treatment of natural products and different types of chemotherapeutic agents in various types of cancer cells, including drug-resistant stable cells. In this study, a significant anticancer mechanism associated with the enhanced anticancer properties of natural products must be elucidated using common cell-based methods such as Western blot analysis.

In addition, unknown signal transduction mediators involved in the enhanced anticancer mechanism by combination treatment may be identified through proteomic analysis. Especially, the enhanced anticancer properties of natural products through combination treatment may be proven by investigating the effects of potential inhibitors. These results could be used for a new chemotherapeutic strategy to improve anticancer efficacy with low toxicity in various types of cancer treatments and to overcome drug resistance. We look forward to your cooperation in this Special Issue.

Dr. Won Sup Lee
Dr. Eun Joo Jung
Guest Editors

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Keywords

  • natural products
  • anticancer properties
  • chemotherapeutc agent
  • combination treatment
  • enhanced anticancer mechanism
  • signal transduction mediators
  • inhibitor effect
  • drug resistance
  • chemotherapy

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