Enhanced Anticancer Properties of Natural Products

Dear Colleagues,

Natural products derived from plants demonstrate various biological activities, including antioxidant, anti-inflammatory, and anticancer properties, depending on their chemical structure and cellular circumstance. Recent studies suggest that the combination treatment of anticancer drugs with lower toxicity may be a more effective chemotherapeutic strategy than single treatment of a high dosage. The aim of this Special Issue is to reveal the enhanced anticancer properties of natural products using a new combination treatment of natural products and different types of chemotherapeutic agents in various types of cancer cells, including drug-resistant stable cells. In this study, a significant anticancer mechanism associated with the enhanced anticancer properties of natural products must be elucidated using common cell-based methods such as Western blot analysis.

In addition, unknown signal transduction mediators involved in the enhanced anticancer mechanism by combination treatment may be identified through proteomic analysis. Especially, the enhanced anticancer properties of natural products through combination treatment may be proven by investigating the effects of potential inhibitors. These results could be used for a new chemotherapeutic strategy to improve anticancer efficacy with low toxicity in various types of cancer treatments and to overcome drug resistance. We look forward to your cooperation in this Special Issue.

Dr. Won Sup Lee
Dr. Eun Joo Jung
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.