Antibiotic Resistance: Appearance, Evolution, and Spread 2.0

Dear Colleagues,

The containment of the development and spread of antibiotic resistance is nowadays one of the major worldwide challenges for the maintenance of human health. If a continuous increase in antibiotic resistance occurs, public health services are expected to enter into the so-called postantibiotic era in a few decades, a situation similar to the one before the discovery of antibiotics. For years, most studies on antibiotic resistance have focused on clinical settings, while antibiotic resistance and transfer have been broadly seen everywhere in the environment. Therefore, studies on this topic have to be broadened to all environmental-, animal-, and human-associated ecosystems.

Understanding the molecular mechanisms involved in the promotion, evolution, distribution, and dissemination of antibiotic resistance in different niches is pivotal, as this might help to obtain scientific knowledge to fight against the appearance and/or spread of resistance. Therefore, we invite authors to submit articles to this Special Issue that will include new and updated principles on these matters from a multihierarchical viewpoint encompassing studies on ecology, molecular biology, and genetics of resistant populations, resistant bacteria, mobile genetic elements, and resistance transfer mechanisms. The integration of data from the application of multiomic approaches, such as genomics, transcriptomics, metagenomics, metatranscriptomics, etc, are of great relevance. However, pure clinical studies are not suitable for this issue, but clinical submissions with molecular experiments are welcomed.

Dr. Baltasar Mayo
Dr. Ana Belén Flórez
Guest Editors

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