Molecular Mechanisms of Arbovirus-Host-Vector Interaction

Dear Colleagues,

Arboviruses have evolved multiple ways to combat the defences of both their host and vector species. These mechanisms are essential in order for the virus to replicate successfully and establish productive infections in the cells of two very different groups, vertebrates (hosts) and invertebrates (vectors). The interactions between arboviral pathogens and their hosts, or vectors are emerging as a key area of infectious disease research, affecting the emergence, epidemiology and severity of clinical disease, caused by these increasingly important pathogens.This Special Issue will include scientific papers concerning interdisciplinary research that will add to our existing knowledge concerning arbovirus-host-vector interactions, as well as review articles that summarize state of the art information, providing further insights into the complex interplay within the three-way relationships between the arbovirus, their hosts, and vectors. These publications will include (but are not limited to) studies that enhance our understanding of the structure-function relationships between arboviral and host/vector macromolecules; the evolutionary genetics/genomics of arboviruses; their capacity to overcome host/vector barriers; their use of host-cell pathways to promote their own replication and the mechanisms they use to avoid sensing by cell defences, subverting the immune system in both the mammalian host and the arthropod vector.

Dr. Houssam Attoui
Prof. Dr. Peter Mertens
Guest Editors

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