Advances in Cancer Epigenetics for Precision Medicine
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 31 May 2026
Special Issue Editors
Interests: oncology; epigenetics; computational biology; ferroptosis; genomics; translational medicine; drug resistance; tumor microenvironment; microbiota
Special Issues, Collections and Topics in MDPI journals
2. Research Center for Prevention, Diagnosis and Treatment of Cancer, University of Catania, 95123 Catania, Italy
Interests: oncology; melanoma; bioinformatics; immunotherapy; ferroptosis; DNA methylation; tumor microenvironment; cancer biomarkers; cancer treatment response
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer epigenetics has recently emerged as a fundamental regulator in precision oncology, complementing genomic profiling to provide molecular insights into mechanisms that regulate gene expression, therapeutic response, and the immune landscape. Among epigenetic mechanisms, DNA methylation stands out as one of the most well-established processes, with clinical implications for early diagnosis, molecular classification, and prognosis across multiple tumor types. In this field, the development of high-throughput sequencing technologies, including long-read methylation profiling and single-cell epigenomic approaches, has significantly enhanced our understanding of the interplay between methylation dynamics and the tumor microenvironment. These advances have uncovered novel aberrant methylation signatures and potential targets that can be exploited therapeutically. However, key challenges remain, including the lack of standardized analytical frameworks for the analysis of methylation data and the translation of complex methylation patterns into robust clinical biomarkers and therapeutic targets.
This Special Issue, “Advances in Cancer Epigenetics for Precision Medicine”, aims to address this gap by showcasing cutting-edge research and innovative methodologies based on epigenetic mechanisms, especially DNA methylation, to improve cancer diagnosis and therapy for personalized cancer care. It will contain original research articles, including in silico studies, in vitro and in vivo experiments, as well as literature reviews.
We look forward to your contributions.
Dr. Alessandro Lavoro
Dr. Saverio Candido
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer epigenetics
- DNA methylation
- precision medicine
- cancer biomarker
- therapeutic target
- epidrugs
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
