Advances in Cancer Epigenetics for Precision Medicine
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 25 December 2026 | Viewed by 1847
Editors
Interests: oncology; epigenetics; computational biology; ferroptosis; genomics; translational medicine; drug resistance; tumor microenvironment; microbiota
Special Issues, Collections and Topics in MDPI journals
2. Research Center for Prevention, Diagnosis and Treatment of Cancer, University of Catania, 95123 Catania, Italy
Interests: oncology; melanoma; bioinformatics; immunotherapy; ferroptosis; DNA methylation; tumor microenvironment; cancer biomarkers; cancer treatment response
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer epigenetics has recently emerged as a fundamental regulator in precision oncology, complementing genomic profiling to provide molecular insights into mechanisms that regulate gene expression, therapeutic response, and the immune landscape. Among epigenetic mechanisms, DNA methylation stands out as one of the most well-established processes, with clinical implications for early diagnosis, molecular classification, and prognosis across multiple tumor types. In this field, the development of high-throughput sequencing technologies, including long-read methylation profiling and single-cell epigenomic approaches, has significantly enhanced our understanding of the interplay between methylation dynamics and the tumor microenvironment. These advances have uncovered novel aberrant methylation signatures and potential targets that can be exploited therapeutically. However, key challenges remain, including the lack of standardized analytical frameworks for the analysis of methylation data and the translation of complex methylation patterns into robust clinical biomarkers and therapeutic targets.
This Special Issue, “Advances in Cancer Epigenetics for Precision Medicine”, aims to address this gap by showcasing cutting-edge research and innovative methodologies based on epigenetic mechanisms, especially DNA methylation, to improve cancer diagnosis and therapy for personalized cancer care. It will contain original research articles, including in silico studies, in vitro and in vivo experiments, as well as literature reviews.
We look forward to your contributions.
Dr. Alessandro Lavoro
Dr. Saverio Candido
Guest Editors
Manuscript Submission Information
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Keywords
- cancer epigenetics
- DNA methylation
- precision medicine
- cancer biomarker
- therapeutic target
- epidrugs
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