New Research Insights in Cystic Fibrosis and CFTR-Related Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 1005
Special Issue Editor
Special Issue Information
Dear Colleagues,
Cystic fibrosis (CF) is caused by the congenital loss of function of the CF transmembrane conductance regulator (CFTR), a cAMP-regulated anion channel expressed within the plasma membrane of epithelial cells. Dysregulated CFTR function caused by genetic and/or environmental stresses can contribute to the pathogenesis of various diseases, including chronic obstructive pulmonary disease (COPD) and bronchiectasis. The landscape of CF has changed significantly over the past 30 years since the identification of the CFTR gene and the advent of CFTR-modulating drugs. Current research aims to improve our understanding of disease pathogenesis in the era of CFTR modulation. This includes new insights into the direct and indirect influences of CFTR modulation on the airway milieu, including resident pathogens, inflammation, and inflammatory cell function.
This Special Issue on the “New Research Insights in Cystic Fibrosis and CFTR-Related Diseases” will gather reviews and original articles that provide novel insights into the immune landscape of respiratory disease, as well as report on groundbreaking therapeutic approaches at the basic, translational, and clinical levels.
Papers investigating CFTR-related and other respiratory diseases with inherent signaling defects and pronounced immune responses are welcome, particularly biomolecular and clinical studies providing expert insights into the advances in the respiratory research field.
Dr. Judith A. Coppinger
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cystic fibrosis
- CFTR related diseases
- COPD
- immune cells
- extracellular vesicles
- neutrophils
- therapeutics
- biomarkers
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
