Role of Interleukins in Cutaneous Diseases and Novel Therapeutic Approaches
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 14237
Special Issue Editor
Interests: skin; basal cell carcinoma; squamous cell carcinoma; dermatology imaging; photodynamic therapy (PDT); phototherapy; skin cancer; biopsy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Interleukins are a large group of immunomodulatory proteins that elicit a wide variety of responses in cells and tissues. Interleukins initiate a response by binding to high-affinity receptors located on the surface of cells thus exerting various physiological activities. Interleukin production pathways, gene regulation mechanisms, receptor systems, and signal transduction have been investigated. In the last decade, interleukins have been shown to play a central role in the pathogenesis of various skin diseases, including atopic dermatitis, psoriasis, chronic spontaneous urticaria, systemic lupus erythematosus, systemic sclerosis and cancer. Moreover, it is now becoming clear that interleukins are involved in biological responses before the onset of disease, not only in intercellular networks but also in interorgan ones. Moving through this complex scenario, some of these molecules have been already studied as novel biomarkers for specific targeted therapies. New studies investigating the role of these molecules as part of a complex and wide biological net are needed to better understand their role in biological systems.
This Special Issue proposal focuses on the role of interleukins in the pathogenesis of skin diseases and their possible role as novel therapeutic targets. Potential topics include, but are not limited to:
- Research roles of interleukins in the pathogenesis of conditions of high social interest
- Possible therapeutic role of interleukins and biological drugs directed towards them
- Possible cross links between different conditions that present similar cytokine profile
- Possible role of physiological and pathological variations of interleukin sequence
- Role of systemic conditions in the expression of specific cytokines
- Role of external and internal environment in cytokine production and disease course
- Define signal cascade to allow blockade of interleukins at various levels depending on patient general conditions
Dr. Francesco Borgia
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- interleukin
- skin diseases
- Th-1
- Th2
- T-cells
- immune system
- immunological disease
- biological drugs
- psoriasis
- atopic dermatitis
- systemic lupus erythematosus
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
