Single-Cell Multi-Omics of Inflammatory Diseases: From Molecular Mechanisms to Precision Medicine
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Informatics".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 99
Special Issue Editor
Interests: tumor microenvironment; drug resistance; immunotherapy; cell engineering; gene therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Recent advancements in single-cell multi-omic technologies have revolutionized our understanding of the complex cellular landscapes underlying chronic inflammatory diseases. By integrating transcriptomic, epigenomic, and proteomic data at single-cell resolution, researchers can now map the molecular dynamics of cellular crosstalk and tissue remodeling with unprecedented detail.
This Special Issue aims to highlight innovative bioinformatic approaches and molecular studies that decipher the heterogeneity of immune and non-immune cells in inflammatory niches. We welcome original research and reviews focusing on:
- Novel computational algorithms for multi-modal data integration.
- Molecular mechanisms of cell–cell communication in chronic inflammation.
- Identification of single-cell biomarkers for disease stratification and therapeutic response.
- Spatial transcriptomics and the architecture of the inflammatory microenvironment.
By bridging the gap between high-dimensional data and clinical application, this collection seeks to pave the way for single-cell-informed precision medicine.
Dr. Patrick Ming-Kuen Tang
Guest Editor
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Keywords
- single-cell bioinformatics
- inflammatory diseases
- molecular interaction
- cellular crosstalk
- precision medicine
- spatial transcriptomics
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