The Relevance of Lipid Metabolism in Viral Hepatitis and Hepatocellular Carcinoma
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (20 April 2025) | Viewed by 1392
Special Issue Editor
2. Medizinische Klinik 1, University Hospital, Goethe University Frankfurt am Main, 60590 Frankfurt, Germany
Interests: sphingolipid; ceramide; HCC; viral hepatitis; cirrhosis; liver failure; sphingomyelinase; exosomes
Special Issue Information
Dear Colleagues,
Unexpected progress has been achieved in recent years with the approval of novel medications for the treatment of hepatocellular carcinoma (HCC). Yet, the enthusiasm around the availability of new compounds is not coupled with a significant improvement in the survival of respective patients. Viral hepatitis, a major cause of HCC worldwide, is resource-dependently adequately addressed; however, even after the sufficient suppression or even eradication of the viral infection, the emergence of HCC is still possible. Both underlying mechanistic interactions as well as efficient biomarkers are lacking in order to properly tailor early diagnosis and effective treatment. In the last two decades, lipid compounds have been under the spotlight since both viral hepatitis as well as HCC seem to interact with the abundant hepatic lipid microenvironment and thus regulate liver inflammation, fibrosis and carcinogenesis.
In this Special Issue, we aim to attract original papers and reviews offering novel insights into the significance of lipid metabolism in viral hepatitis and HCC, providing an interesting discussion.
Dr. Georgios Grammatikos
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- sphingolipid
- ceramide
- HCC
- viral hepatitis
- sphingomyelinase
- exosomes
- immune therapy
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
