Calcium Metabolism and Regulation
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 943
Special Issue Editors
Interests: nephrocalcinosis; nephrolithiasis; vascular calcification; calciphylaxis; calcifying skin disorders; vitamin D; parathyroid hormone; sodium thiosulfate; CKD-MBD; vitamin K2; myoinositol-hexaphosphate; oxidative stress
Interests: apoptosis; clinical cardiology; heart failure; hypertension; cell culture; ELISA; echocardiography; flow cytometry; atrial fibrillation; atherosclerosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Calcium has multiple roles in biology, including cell signaling, motor function, and bone mineralization. Regulation of calcium homeostasis includes maintenance of normal blood levels, bone mineralization and inhibition of extraosseous depositions, neuronal and muscular function, intracellular compartmentation, shifting, and signaling. On a systemic level, this involves complex hormonal regulation of calcium and interconnected phosphate metabolism, prevention of mineral precipitation by a multi-factorial balance between promoters and inhibitors of calcification, and targeted transport mechanisms from soft tissues to bone structures. On a tissue level, local activation of specific proteins and enzymes may influence mineral deposition. On a cellular and subcellular level, it comprises regulation of calcium flux via ion channels and intracellular calcium shifts, as well as interaction with calcium-binding proteins for activation of further proteins and membrane functions. This Special Issue aims to give a scope of new developments in various areas of physiological and pathological calcium metabolism and regulation, including osteogenic transdifferentiation, the formation of pathological mineral depositions, and candidate molecules for the treatment of calcifying disorders.
So we would like to cordially invite you to contribute new scientific discoveries to this fascinating and multi-facetted field of research.
Dr. Hermann Salmhofer
Dr. Michael Lichtenauer
Guest Editors
Manuscript Submission Information
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Keywords
- pathologic calcification
- calcification inhibitors
- calciprotein particles
- Runx-2
- apatite
- matrix Gla protein
- fetuin-A
- vitamin D
- parathyroid hormone
