Toxicants and Their Effects on Innate Immune Function and Inflammatory Response
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".
Deadline for manuscript submissions: 20 November 2025 | Viewed by 892
Special Issue Editor
Interests: aging; endocrinology; comparative physiology; animal models; cell biology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Toxicants such as pesticides and plasticizing agents have become ubiquitous in both terrestrial and aquatic environments. Although the effects of these man-made substances on reproductive and metabolic functions have been studied thoroughly, how they may impact other aspects of physiological functions are not as well known. For example, innate immune function serves as a critical line of defense against pathogens in both invertebrates and vertebrates, and there is mounting evidence that exposure to various toxicants may significantly impair innate immune function in multiple species. In addition, within vertebrates, the inflammatory response is an important component of an innate immune response, and it is also an important mediator of the effects of tissue injury. As with innate immune function, in general, there are data suggesting that the inflammatory response is significantly altered by exposure to various toxicants. The purpose of this Special Issue is to highlight the impact of environmental pollutants on innate immune function and the inflammatory response in both invertebrate and vertebrate animal models.
Dr. James M. Harper
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- ecotoxicology
- innate immunity
- inflammation
- pesticides
- plasticizers
- pattern-recognition receptors
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
