Role of Natural Products and Derivatives in Tumor
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (30 January 2024) | Viewed by 3974
Special Issue Editor
Interests: ROS; calcium; ER stress; NOX; apoptosis; cell death; natural products; phytochemicals; plant antioxidants; cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Inflammation is related with the development of cancer. Chronic inflammation has been associated with cancer and tumorigenesis such as survival, tumor promotion, proliferation, resistance, invasion, cellular transformation, metastasis, and angiogenesis. Inflammation-mediated cancer can be caused various mutation types to multifunction of tumor suppressors or oncogenes. Moreover, it is results in the secretion of pro-inflammatory cytokines and chemokines by immune or cancer cells. Recently, natural products and their derivatives have potential roles in the development of new drugs and pharmaceutical strategy against cancer, immune disease, and chronic inflammation, etc. Increased research reported anti-cancer and anti-inflammatory natural products including polysaccharides, saponins, capsaicin, polyphenols, terpenoids, etc and then they have potential immunomodulatory effects in cancer and inflammatory disease. The immunoregulation mechanisms of natural products and their derivatives are involved diverse signal transduction pathway against cancer and inflammatory diseases. However, there is still a considerable obstacle in treating natural products and their derivatives as novel therapeutic strategies.
This Special Issue of IJMS, “Role of Natural Products and Derivatives in Tumor” will focus on the new advance therapeutic strategies to overcome inflammation and cancer by natural products and active compounds in various immune or cancer models. Therefore, we will suggest progress in the understanding of various signal transduction pathway and focus on therapeutic approaches to develop new treatments to overcome inflammation and cancer.
Dr. Tae Woo Kim
Guest Editor
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