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Platelet-Based Biomaterials in Regenerative Medicine: Biochemical Insights and Therapeutic Perspectives

A Special Issue of International Journal of Molecular Sciences (ISSN 1422-0067) belonging to the section "Biochemistry".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 234

Editors


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Guest Editor
Department of Veterinary Medicine and Animal Production University of Naples Federico II, via Federico Delpino 1, 80137 Napoli, Italy
Interests: veterinary medicine; horse surgery; A-PRF+
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Guest Editor Assistant
Department of Pharmacy, University of Salerno, Via G. Paolo II, 84084 Fisciano, Italy
Interests: antioxidants; biochemistry of nutrition; in vivo and in vitro studies

Special Issue Information

Dear Colleagues,

Platelet-based biomaterials have emerged as promising tools in regenerative medicine due to their ability to promote tissue repair, modulate inflammation, and support healing processes through the release of growth factors and bioactive molecules. Among these, platelet-rich plasma (PRP), platelet-rich fibrin (PRF), and related platelet concentrates are increasingly being investigated in both human and veterinary medicine for their therapeutic and translational potential. Continuous advances in relation to the preparation protocols, biological characterization, and mechanistic understanding of platelet-based biomaterials are expanding their applications across different medical fields. This Special Issue aims to provide a comprehensive platform for advancing the understanding of the biochemical mechanisms underlying platelet-derived biomaterials and their role in regenerative processes. We welcome original research articles and reviews exploring their biological properties, preparation strategies, and mechanistic pathways, with a strong emphasis on studies that elucidate novel biochemical mechanisms.

Both in vitro studies that uncover cellular and molecular mechanisms, as well as in vivo preclinical investigations and clinical studies, are encouraged to provide a complete translational perspective on their therapeutic potential. Contributions addressing veterinary applications and cross-species translational insights are also highly welcome.

We look forward to receiving your contributions.

Dr. Vincenzo Vestuto
Prof. Dr. Maria Pia Pasolini
Guest Editors

Dr. Maria Rosaria Miranda
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • PRP
  • PRF
  • platelet-based biomaterials
  • regenerative medicine
  • tissue regeneration
  • biochemical pathways
  • biomaterials
  • translational medicine
  • clinical biochemistry

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Published Papers

This special issue is now open for submission.
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