Antioxidants: Design, Synthesis, and Mechanism of Actions
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Macromolecules".
Deadline for manuscript submissions: 20 February 2026 | Viewed by 458
Special Issue Editor
Special Issue Information
Dear Colleagues,
Antioxidants are essential compounds that protect cells from oxidative damage caused by free radicals and reactive oxygen species. They play a significant role in slowing the aging process and reducing the risk of chronic diseases. Antioxidants are also widely used in other applications such as food preservation, cosmetics, and pharmaceuticals. To ensure their successful use across multiple fields, it is crucial to develop antioxidants that maintain their effectiveness while remaining safe.
This Special Issue invites submissions on the innovative design and synthesis of next-generation antioxidants that exhibit strong activity with minimal pro-oxidant effects. Potential topics include phenolic, thiolic, or nitrogen-based free radical scavengers, inhibitors of oxidant-generating enzymes, activators of antioxidant-generating enzymes, metal chelators, and multifunctional antioxidants, all of which should undergo rigorous testing for efficacy.
We also welcome research on antioxidant mechanisms, testing in cell lines and animal models, and the exploration of new methods to enhance the water solubility of hydrophobic antioxidants. Join us in advancing this important field!
Prof. Dr. Choon Young Lee
Guest Editor
Manuscript Submission Information
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Keywords
- antioxidant synthesis
- multifunctional antioxidants
- oxidant-generating enzyme inhibitors
- activators of antioxidant-generating enzymes
- phenolic antioxidant
- thiol-based antioxidant
- nitrogen-based antioxidants
- anti-inflammatory
- oxidative stress
- free radical scavenging
- reactive oxygen species
- reactive nitrogen species
- mechanisms of action
- metal chelator
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