Organoids: The New 3D-Frontier to Model Different Diseases In Vitro

Dear Colleagues, 

Organoids are miniaturized replicates of human organs that recreate their architecture and physiology. They are generated from patient biopsy samples or from induced pluripotent stem cells and provide an unprecedented tool to model organogenesis and human diseases. Organoids have been used to study genetic disorders and infectious diseases as well as for drug screening. They represent a valid alternative or complement to animal models, because it is complex to extrapolate results from model systems to humans. On the other hand, it is well known that biological processes specific to the human body cannot be modelled in other animals. Moreover, organoids might become a useful tool in the perspective of personalized medicine and therapy.

This Special Issue calls for papers presenting the implementation of organoid technology and offering novel insights into organogenesis, as well as into the pathophysiology of diseases.

Dr. Alessandra Cazzaniga
Dr. Sara Castiglioni
Guest Editors

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