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Molecular Metabolism in Plant Chemistry

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: closed (20 July 2025) | Viewed by 1969

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Laboratory of Pharmacognosy, School of Pharmacy, Faculty of Health Science, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
Interests: medicinal and aromatic plant; bioactive compounds; chromatography; spectroscopy; antioxidant activity; phenolic compounds; bioactivity; chemistry of natural substances; isolation, structural determination, characterization and biological evaluation of potentially interesting; secondary metabolites for pharmaceutical; alimentary and cosmetic fields; food chemistry; essential oils from aromatic plants
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Special Issue Information

Dear Colleagues,

The molecular metabolism of plants involves a comprehensive examination of the structure, function, and interactions of various compounds within plant systems and their critical roles in growth, development, defense mechanisms, and ecological relationships. Phytochemicals, including antioxidants, flavonoids, and essential oils, contribute significantly to enhancing the flavor, color, and health benefits of food products.

A deep understanding of the chemical defenses that plants produce is essential for developing crops that exhibit greater resistance to pests and diseases. The study of plant metabolism facilitates the creation of crops with improved nutritional profiles, enhanced stress tolerance, and increased yields. Furthermore, molecular metabolism aids in the identification and synthesis of novel plant-derived compounds with potential therapeutic applications.

In summary, molecular metabolism in phytochemistry focuses on the intricate biochemical processes that occur within plants, encompassing metabolic pathways, the biosynthesis of secondary metabolites, the functions of plant hormones, and their interactions with their surrounding environment. This field holds significant promise for advancements in agriculture, medicine, biotechnology, and environmental science.

This Special Issue is supervised by Prof. Lazari Diamanto, who is assisted by Dr. Olga Tsiftsoglou.

Prof. Dr. Diamanto Lazari
Guest Editor

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Keywords

  • phytochemistry
  • plant secondary metabolism
  • biosynthesis of secondary metabolites
  • plant and pathogens
  • stress tolerance and resistance
  • plant cell cultures
  • plant biotechnology
  • bioactive natural products

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Published Papers (1 paper)

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Research

13 pages, 9451 KB  
Article
Volatile Flavoromics of Four Mesona chinensis Benth Cultivars: Metabolomic Basis for the Superior Aroma of the Zengcheng Elite Cultivar
by Yuqing Niu, Yujing Zhu, Meixia Zheng, Yanming Zhu, Hong Chen, Dagang Tian and Hailan Su
Int. J. Mol. Sci. 2025, 26(17), 8713; https://doi.org/10.3390/ijms26178713 - 7 Sep 2025
Viewed by 1165
Abstract
Zengcheng (ZC), a superior cultivar of Mesona chinensis Benth, is distinguished by its unique sensory attributes and exceptional phytochemical quality, rendering it the cultivar of choice for commercial production. In this investigation, we employed comprehensive targeted metabolomics to systematically delineate the volatile metabolome [...] Read more.
Zengcheng (ZC), a superior cultivar of Mesona chinensis Benth, is distinguished by its unique sensory attributes and exceptional phytochemical quality, rendering it the cultivar of choice for commercial production. In this investigation, we employed comprehensive targeted metabolomics to systematically delineate the volatile metabolome of ZC in comparison to three relevant counterparts grown under uniform field conditions and harvested at the same developmental stage. Our primary objectives were to (i) quantitatively characterize the metabolomic divergence between ZC and the comparative cultivars, and (ii) elucidate the molecular basis underlying ZC’s characteristic flavor signature. Through high-throughput gas chromatography–mass spectrometry (GC-MS) analysis, a total of 1767 volatile metabolites were confidently annotated, with terpenoids and esters identified as the predominant chemical classes. Notably, ZC exhibited significantly elevated levels of terpenoids, esters, and aldehydes, which collectively conferred an intensified green, sweet, herbal, and fruity aroma. Key discriminatory metabolites included geranyl formate and geranic acid (imparting a pronounced green note), which were identified as pivotal determinants of ZC’s unique flavor profile. These findings provide mechanistic insights into the biochemical pathways governing flavor development in M. chinensis Benth and establish a robust foundation for precision-breeding strategies aimed at enhancing sensory quality and developing elite cultivars. Full article
(This article belongs to the Special Issue Molecular Metabolism in Plant Chemistry)
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