Effects of Natural Bioactive Compounds on Cellular Responses
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 58
Special Issue Editor
2. Centre for Research and Technology of Agro-Environmental and Biological Sciences (CITAB-UTAD), 5000-801 Vila Real, Portugal
Interests: cell biology; biochemistry; cell-based assays; evaluation of bioactivities of natural compounds; phytochemicals; nutraceuticals
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Natural bioactive compounds are biologically active molecules that have the potential to affect positively or negatively the cell activity. These compounds comprise a plethora of molecules produced by living organisms, such as plants, fungi, bacteria, marine organisms, and reptiles; that target specific cellular components (e.g., ion channels, receptors, enzymes, and others), changing cell and organ behavior. Examples of natural bioactive compounds include polyphenols, alkaloids, vitamins, peptides, oligosaccharides, terpenoids, and others. The response of cells challenged by these molecules can occur through their modulating action on various cellular pathways, resulting in toxicologically or pharmacologically relevant effects. Among the relevant effects, we highlight the anti-inflammatory, antimicrobial, anticancer, antioxidant, and neuroprotective actions, but others could be mentioned. Discovering these natural molecules, as well as understanding the specific changes they induce in target cells, is a major challenge in the search for new therapeutic molecules.
This Special Issue aims to comprehensively highlight the newest discoveries on natural bioactive compounds, their cellular targets and cellular responses, and their physiological and pharmacological roles.
We cordially invite authors to contribute original articles, as well as reviews, that bring new insights into the characterization of specific cellular responses promoted by the action of natural bioactive compounds.
Prof. Dr. Amélia M. Silva
Guest Editor
Manuscript Submission Information
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Keywords
- cellular targets
- cell proliferation
- cell death mechanisms
- cell signalling
- cytokines
- vitamins
- phytochemicals
- venoms
- peptides
- pharmacological effect
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