Editorial Board Members’ Collection Series: Iron Homeostasis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: 20 March 2025 | Viewed by 6105
Special Issue Editors
Interests: iron metabolism; ferritin; iron storage
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Iron is essential for almost all living organisms since it is involved in critical biochemical processes such as the transport of oxygen, respiration, synthesis and repair of DNA, amongst others. However, iron is also potentially toxic when in excess or deregulated, and its dysregulation can lead to severe health consequences. The dynamic equilibrium of iron homeostasis within the body is governed by a complex regulated interplay of absorption, transport, utilization, and storage mechanisms. Thus, iron metabolism involves the study of its absorption, transport, utilization, storage, emerging roles of iron in inflammation, cellular signaling, and the relationship with the microbiome. It includes iron overload and iron-deficient diseases and examination to develop new and efficient therapies. Of importance, iron is involved in ferroptosis, a non-apoptotic programmed death mechanism that plays a role In cancer, neurodegeneration, and various other pathologies. This special Issue aims to present the latest research or new views on human iron metabolism, and original research articles and comprehensive reviews are welcomed.
Prof. Dr. Paolo Arosio
Dr. Antonella Roetto
Guest Editors
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Keywords
- iron metabolism
- iron homeostasis
- iron-deficient diseases
- iron overload
- ferroptosis
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