Exploring the Glioblastoma Complexity: New Perspectives in the Molecular and Imaging Fields

Dear Colleagues,

Glioblastoma (GBM), despite the advances in surgical resection, chemotherapy (temozolomide) and radiotherapy treatment, remains one of the most fatal tumors. The fight against GBM is made even more difficult by the GBM inter and intra heterogeneity, the presence of the blood–brain barrier and the molecular characteristics of the peritumoral region. Achieving effective outcomes against GBM increasingly requires the integration of imaging and molecular techniques that enable the early diagnosis of GBM and monitoring of GBM response to treatments. In particular, recent advances have been achieved in circRNA, lncRNA, ctDNA and extracellular vesicles characterized by liquid biopsy.

This Special Issue, “Exploring the Glioblastoma Complexity: New Perspectives in the Molecular and Imaging Fields”, will cover a selection of recent research topics and current review articles in the field of imaging and molecular characterization, taking into consideration data obtained both in animal models and in vitro (neurospheres, organoids) and also data on the possible diagnostic biomarkers obtained by liquid biopsy or using innovative imaging techniques.

Prof. Dr. Angela Bentivegna
Dr. Gabriella Nicolini
Guest Editors

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