Molecular Mechanisms of Human Liver Diseases: 3rd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 724
Special Issue Editor
Interests: oxidative stress; cardiac function; mitochondrial function; aging; nitric oxide; physiology; NAFLD; microvesicles
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
There are many known liver diseases, the most prominent of which are virus-induced and autoimmune hepatitis, non-alcoholic fatty liver disease (NAFLD), storage diseases such as Wilson’s disease and hemochromatosis, and acute and chronic liver failure.
NAFLD, which includes steatohepatitis (in particular, non-alcoholic steatohepatitis (NASH), which should be separated from alcoholic steatohepatitis (ASH)) and steatosis, is a rising health problem worldwide. Steatosis, liver fibrosis, and cirrhosis often develop into hepatocellular carcinogenesis, frequently resulting in the need for liver transplantation, which underlines the clinical significance of this disease complex.
Wilson’s disease (which involves morbidly heightened copper accumulation) and hemochromatosis can also both result in cirrhosis. Whereas acute liver failure can have multiple origins over a short period of time, chronic liver failure is preceded by HBV, HCV, or excessive alcohol intake over a long time span.
In this Special Issue, we provide an overview of current knowledge and recent findings regarding the development, progression, molecular pathways, and mechanisms of these diseases.
Dr. Elena Grossini
Guest Editor
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Keywords
- non-alcoholic fatty liver disease (NAFLD)
- non-alcoholic steatohepatitis (NASH)
- alcoholic steatohepatitis (ASH)
- Wilson’s disease
- hemochromatosis
- viral hepatitis
- autoimmune hepatitis
- hepatocellular carcinoma
- signaling pathways
- molecular mechanisms
- metabolic dysfunction-associated steatotic liver disease (MASLD)
- metabolic dysfunction-associated steatohepatitis (MASH)
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